Long-term use of rosuvastatin can not ignore these side effects.

Original Dr. Wang Cardiovascular Doctor Wang Cardiovascular Doctor Wang

Every time Dr. Wang finishes prescribing statins in the outpatient department, he must tell the patients a few more words: Be sure to check again! Don’t have side effects that were not found in time!

Cardiovascular and cerebrovascular diseases have become the number one killer endangering our lives and health. Preventing and treating cardiovascular and cerebrovascular diseases is almost related to every family, because the number of cardiovascular diseases in China has reached 330 million at present, including 11 million coronary heart disease and 13 million stroke, so each of us is more or less inextricably linked with cardiovascular and cerebrovascular diseases.

Statins, as the cornerstone drugs for the prevention and treatment of cardiovascular and cerebrovascular diseases, have attracted more and more attention. On the one hand, statins can bring benefits to more patients, on the other hand, the side effects of statins must be paid enough attention.

As a representative of the third generation statins, rosuvastatin is gradually known by people.

Rosuvastatin is a lipid-regulating drug and an inhibitor of 3- hydroxy -3-methylglutaryl-CoA (HMG-CoA) reductase. Rosuvastatin can inhibit cholesterol synthesis and reduce blood lipid level, especially low-density lipoprotein. Rosuvastatin has the effects of stabilizing plaque, anti-inflammation and improving endothelial function, and it is one of the long-term drugs for patients with coronary heart disease and stroke.

In short, what benefits can rosuvastatin bring to us?

Reduce cholesterol, low density lipoprotein and triglyceride; At the same time, it can increase high density lipoprotein. Rosuvastatin also has the function of preventing and treating cardiovascular and cerebrovascular diseases.

Friends who take rosuvastatin for a long time are nothing more than dyslipidemia or to prevent and treat cardiovascular and cerebrovascular diseases. Moreover, patients with abnormal cholesterol or cardiovascular and cerebrovascular diseases generally need to take statins for a long time, because even if statins can reduce cholesterol and return to normal, once they stop taking drugs, their blood lipids will be abnormal again; Just like taking antihypertensive drugs for a long time for hypertension and taking hypoglycemic drugs for a long time for diabetes.

Of course, the emphasis is on coronary heart disease, cerebral infarction and other diseases. Even if blood lipids are normal, statins should be taken for a long time, because it is mentioned above that statins are not only lipid-regulating drugs, but also drugs that stabilize plaques, resist inflammation and improve endothelial function, which can effectively prevent and reduce the risk of cardiovascular and cerebrovascular diseases.

All drugs that need to be taken for a long time are the most troublesome thing for people. Once side effects occur, not only will their diseases not be cured, but they will increase their heart diseases. It is really impossible to catch chickens and eat rice.

Therefore, every time Dr. Wang prescribed rosuvastatin to a patient, he must repeatedly explain what are the side effects of rosuvastatin. What should I pay attention to?

Take rosuvastatin need to pay attention to:

1. If it is not for emergency use before taking it, it is best to check a liver function, four blood lipids, blood sugar and muscle enzymes.

2. Take liver function, blood lipid, blood sugar and muscle enzyme within 3 months.

A, if the transaminase is 3 times higher than the normal value, you should stop using this product or reduce it, because rosuvastatin will cause liver damage, which will lead to the increase of transaminase, especially in the first three months.

B. Attention should also be paid to the increase of muscle enzyme. It is generally suggested that the muscle enzyme should be stopped when it is increased by 10 times. However, once the muscle enzyme is found to be increased in clinic, we dare not wait until it is increased by 10 times, so we will stop taking the drug as soon as possible and observe. Stop using this product immediately when myalgia and myasthenia occur for unknown reasons or suspected myopathy, and check the muscle enzymes as soon as possible. Because statins cause muscle damage is a common side effect.

C, if blood sugar rises, it may be that statins are at work, but we can’t stop taking drugs just because rosuvastatin may cause new-onset diabetes. Statins themselves bring us more benefits than new-onset diabetes. Simply understanding statins to prevent 9 cardiovascular and cerebrovascular diseases may lead to 1 diabetes, and if we find that active control of diabetes can also reduce the risk caused by diabetes.

3. It may also occur: pharyngitis, pain, headache, flu-like syndrome, etc.

4. If there is no problem after the review in the first three months, it is recommended to review it once a year in the future.

Who uses it with caution?

Excessive drinkers should use it with caution; Use with caution in patients with a history of liver disease; Use with caution for lactating women.

Who is forbidden?

Statin allergy, active liver disease, myopathy, pregnant women.

Rosuvastatin can indeed bring us many benefits, such as adjusting blood lipids, reducing bad blood lipids, raising good blood lipids, reducing the occurrence of cardiovascular and cerebrovascular diseases, and preventing myocardial infarction and cerebral infarction; But any drug is a double-edged sword. If it is used well, it will help people, but if it is not used well, it will harm people.

Monitoring the side effects of rosuvastatin is very important for friends who take rosuvastatin!

[Copyright of Dr. Cardiovascular King]

Original title: "Cardiologists tell you that these side effects should not be ignored when taking rosuvastatin for a long time"

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