The preferential information of car models is an important reference factor for consumers when buying a car. In order to let everyone know the automobile market where they buy a car in time, we will offer you the price reduction rankings of different levels of cars in plug-in hybrid vehicles to help you grasp the preferential situation of cars in time and buy cars at a lower cost. In the dealer’s quotation on March 18th, the car series such as (|) and Leiling Shuangqing E+, as well as the SUV series such as BMW X1 New Energy and Tanyue GTE plug-in hybrid have higher preferential margins in Foshan, which are worthy of users’ further attention. Next, we will introduce you to the price reduction rankings of cars in various market segments in detail. If you have a car purchase plan in the near future, please follow us to get the most comprehensive discount!

　　Quote Weekly is a program that interprets the automobile market based on the price preference. Relying on the dealer quotation data on the car home platform, it brings users the preferential ranking of different market segments every week. The price data involved in this paper is the quotation data of Foshan dealers on car home platform on March 18th. The preferential conditions of the models introduced in this paper are calculated from the quotation data of all local dealers within the data retrieval date for reference only. Please refer to the actual quotations and preferential conditions of the dealers. The average discount/average discount rate mentioned in this paper is the average of the discount reduction/discount rate of all local dealers selling this model.

Plug-in Hybrid Power-Car Price Reduction Ranking

　　We selected the preferential price information of Foshan dealers on March 18th. At present, the average discount range of the models on sale of Corolla Twin Engine E+, Ralink Twin Engine E+, Volvo S90 New Energy, Magotan GTE Plug-in Hybrid and Volvo S60 New Energy is the highest among cars, with an average discount rate of 14.0%-17.47%.

　　Among them, the average discount rate of Leiling Shuangqing E+ has further increased compared with last week, and interested users may consider contacting the dealer to negotiate; The average discount rate of Corolla Dual Engine E+, Volvo S90 New Energy, Magotan GTE Plug-in Hybrid and Volvo S60 New Energy is the same as last week. Interested users can choose to sell or continue to wait and see the price trend.

　　Among the TOP 5 cars with declining cars, Magotan GTE plug-in hybrid and Volvo S90 new energy have relatively high word-of-mouth scores, and users have a good overall evaluation. At the same time, they have certain preferential space. Users who are considering buying a car but are hesitant to choose a car system may wish to pay attention to this car system, which has certain advantages in terms of preferential margin and word-of-mouth evaluation.

　　Next, let’s take a look at the preferential situation of the specific models for sale in the car series with the highest price drop.

Car Price Reduction Series TOP1: Corolla Twin Engine E+

　　■ Preferential models

　　The models with the highest discount range in the Corolla dual-engine E+ are the 2019 1.8L E-CVT Pioneer Edition, the 2019 1.8L E-CVT Leading Edition and the 2020 1.8L E-CVT Comfort Edition. The average discount rates of dealers’ quotations are 37,700 yuan, 37,700 yuan and 38,300 yuan, with average discount rates of 18.13% and 17.95%.

　　■ Selling dealers

　　For the above models, dealers such as Foshan Longjiang Toyota, Nanhai Guicheng Toyota and Foshan Junan Toyota all sell them. At the same time, we list the corresponding grades of dealers to provide further reference for your car purchase. Interested users can contact the dealer for further consultation.

Plug-in hybrid-SUV price reduction ranking

　　We selected the preferential price information of the SUV of Foshan dealers on March 18th. At present, the average discount range of the models on sale of BMW X1 New Energy, Tanyue GTE Plug-in Hybrid, Volvo XC60 New Energy, Volvo XC90 New Energy and Tiguan L New Energy is the highest among SUVs, with an average discount rate of 11.09%-16.07%.

　　Among them, the average discount rate of Tiguan L New Energy has further increased compared with last week, and interested users may consider contacting dealers to negotiate; The average discount rate of Tanyue GTE plug-in hybrid, Volvo XC60 new energy and Volvo XC90 new energy is the same as last week, and interested users can choose to sell or continue to wait and see the price trend; The average discount rate of BMW X1 New Energy has decreased compared with last week, so interested users can pay more attention to the price information.

　　Among the TOP 5 SUV models, the word-of-mouth score of Volvo XC90 New Energy and Tanyue GTE plug-in hybrid is relatively high, and the overall evaluation of users is good. At the same time, there is a certain preferential space. Users who are considering buying a car but are hesitant to choose a car model may wish to focus on this car model, which has certain advantages in terms of preferential margin and word-of-mouth evaluation.

　　Next, let’s take a look at the preferential situation of the specific models for sale in the car series with the highest price drop.

SUV Price Reduction Series TOP1: BMW X1 New Energy

　　■ Preferential models

　　The models with the highest discount range in BMW X1 new energy are the 2020 xDrive30Le exclusive model and the 2021 xDrive30Le exclusive model. The average discount offered by dealers is 96,400 yuan and 32,100 yuan, and the average discount rates are 24.10% and 8.04%. Interested users can pay more attention.

　　■ Selling dealers

　　For the above models, Shunde Hebao Horse, Dingbaoxing Chancheng BMW 4S Store, Foshan Tongbao Chancheng International Automobile City Store and other dealers all sell them. At the same time, we list the corresponding grades of dealers to provide further reference for your car purchase. Interested users can contact the dealer for further consultation.

Plug-in hybrid-MPV price reduction ranking

　　We selected the MPV preferential price information of Foshan dealers on March 18th. At present, the average discount range of the models sold by SAIC Chase MAXUS EUNIQ 5, Jiaji New Energy and Dajielong PHEV (imported) is the highest among cars, with an average discount rate of 4.02%-5.57%.

　　Among them, the average discount rate of SAIC Chase MAXUS EUNIQ 5, Jiaji New Energy and Dajielong PHEV (imported) is the same as last week, and interested users can choose to sell or continue to wait and see the price trend.

　　Among the TOP 5 cars with MPV decline, the word-of-mouth scores of Dajielong PHEV (imported) and Jiaji New Energy are relatively high, and the overall evaluation of users is good. At the same time, they have certain preferential space. Users who are considering buying a car but are hesitant to choose a car system may wish to focus on this car system. They all have certain advantages in terms of preferential margin and word-of-mouth evaluation.

　　Next, let’s take a look at the preferential situation of the specific models for sale in the car series with the highest price drop.

MPV Price Reduction Car Series TOP1: SAIC Chase MAXUS EUNIQ 5

　　■ Preferential models

　　The models with the highest discount range in MAXUS EUNIQ 5 of SAIC Chase are 2020 1.3T PLUG IN Elite Edition, 2020 1.3T PLUG IN Deluxe Edition and 2020 1.3T PLUG IN Exclusive Edition. The average discounts quoted by dealers are 10,000 yuan, 10,000 yuan and 10,000 yuan, and the average discount rates are 6.03%, 5.56% and 5.11%. Interested.

　　■ Selling dealers

　　For the above models, Foshan Guangwu Baotong, Foshan Yutong Datong and other dealers have sold them, and we have listed the corresponding grades of dealers to provide further reference for your car purchase. Interested users can contact the dealer for further consultation.

　　Have you been moved by this week’s price-cutting car rankings? If there is a car you are interested in here and the price reduction is good, I suggest you take action as soon as possible, buy it early and get benefits early! If the discount rate has not reached your expectation, you can wait and see if there will be any updated preferential activities in the future. The weekly market report continues to bring you price reduction rankings, and I look forward to your continued attention ~

　　How to read the hints your body gives you? What to eat to supplement the most lacking nutrition in the body? Life Times interviewed a number of authoritative nutrition experts to help you get the right medicine.

　　Interviewed experts

　　Ge Keyou, honorary chairman of China Nutrition Society, famous nutritionist and "father of dietary pagoda"

　　Zhai Fengying, Deputy Director of Institute of Nutrition and Food Safety of China Center for Disease Control and Prevention and Secretary General of China Nutrition Society.

　　Chen Xiafei, chief nutritionist of East China Hospital affiliated to Fudan University in Shanghai.

　　Wang Xingguo, Director of Nutrition Department of Dalian Central Hospital.

　　What nutrients are most lacking in Chinese?

　　According to the Report on Nutrition and Chronic Diseases of Residents in China (2015), the intake of cereals and cereals of urban and rural residents in China has remained stable in the past 10 years. The total intake of protein is basically the same, the intake of high-quality protein has increased, and the consumption of beans and milk is still low.

　　Excessive fat intake, the average dietary fat energy supply ratio exceeds 30%. The intake of vegetables and fruits decreased slightly, and some nutrients such as calcium, iron, vitamins A and D were still lacking.

　　1 calcium deficiency

　　According to the third national nutrition survey, what Chinese lacks most at present is calcium. The national average daily intake is less than 400 mg, only reaching RDA (if the human body has insufficient intake of a nutrient for a long time, it will be in danger of deficiency. When the intake reaches a certain value, people are not in danger of developing deficiency. This value is called the RDA value. ) 49.2% of the required 800 mg.

　　All kinds of bone diseases caused by calcium deficiency are common, such as osteoporosis, hand and foot convulsion, bone hypoplasia, rickets and so on. Milk, cheese, eggs, bean products, kelp, seaweed, shrimp skin, sesame, hawthorn, marine fish, vegetables and so on are among the daily foods in the family.

　　2 Iron deficiency

　　At present, the daily iron intake of Chinese residents has reached RDA value, but because the iron intake mainly comes from non-heme iron in rice, nuts, black-leaf vegetables and other plants, its utilization rate and absorption rate are low, far lower than the absorption rate of iron in animal foods. In addition, Chinese residents are used to eating cereals, and cereals contain high concentrations of plant acids, which will obviously inhibit the absorption of iron by human body.

　　Therefore, although the iron intake of Chinese residents is not low, the iron really absorbed by the human body is less, which can not meet the needs of the human body, which makes the residents in China have extensive anemia, especially women, children and the elderly. When the human body is short of iron, it can lead to iron deficiency anemia, with symptoms such as loss of appetite, irritability, fatigue, pale face, palpitation and dizziness.

　　3 vitamin a deficiency

　　The national average daily intake is 476 micrograms (of which 157 micrograms are vitamin A and 319 micrograms are from the transformation of β-carotene), which is only 61.7% of the 800 micrograms required by RDA. The main function of vitamin A is to maintain the visual function in dark light and maintain the health of epithelial cells. People with vitamin A deficiency may have some dry and rough skin, dry eyes and fear of light.

　　4 vitamin d deficiency

　　Xu Hao, director of the Department of Nuclear Medicine of the First Affiliated Hospital of Jinan University, analyzed the investigation of vitamin D status in big cities of China, and said that calcium and vitamin D are the components that directly affect the bone status, while among people (over 20 years old) in big cities of China, only 0.67% have normal vitamin D, and 21% have severe vitamin D deficiency.

　　Vitamin D is a fat-soluble vitamin. It is one of the three hormones that regulate calcium metabolism. It can prevent and treat osteoporosis and rickets in children, which is very important for bone health. Moreover, more and more studies now confirm that its function is far more than that. Recent studies have confirmed that vitamin D deficiency is also related to diabetes, coronary heart disease, hypertension, fatty liver, rheumatoid arthritis, oral diseases, multiple sclerosis and other common chronic diseases.

　　The body is uncomfortable and may be short of nutrients.

　　Here are some small body signals that you can check against. If you find yourself with the same problem, you must adjust your diet in time or take some supplements according to the national recommended standards. It’s still not relieved after three weeks, so it’s better to go to the hospital for examination.

　　Dry eyes, congestion, easy to be nervous.

　　Chen Xiafei, who is short of B vitamins, said that B vitamins are one of the most vulnerable vitamins in Chinese, especially vitamin B2. Dr. Tannin, a member of the Royal Society of General Practitioners, said: 　　

　　"B vitamins can regulate the total amount of fluid in the eye socket. When vitamin B2 is lacking, the blood vessels on the surface of the eyes are easy to be infected, leading to dry eyes, conjunctivitis and red blood." Wang Xingguo told reporters that in fact, vitamin B2 is related to all skin and mucosal diseases, such as oral mucosal ulcers, swollen gums and so on. Once these symptoms appear, it is best to take vitamin B2 first. If it is not good, consider other reasons. In addition, B vitamins can reduce stress, enhance people’s attention and improve cognitive ability. People who lack vitamin B are often nervous.

　　Foods containing vitamin B: dairy products, meat and liver. 　　

　　Daily recommended amount: vitamin B2-1.6 mg for British men and 1.2 mg for British women; China male 1.4 mg, female 1.2 mg. Wang Xingguo pointed out that many foods contain vitamin B2, but none of them are particularly rich, so it is best to take supplements when they may be deficient.

　　Muscle spasm, insomnia and magnesium deficiency

　　Ursula arens said that British people are generally short of magnesium, because their diet is mainly low-magnesium foods such as fast food, soda, potato chips, biscuits and flour and rice. Eating a lot of foods rich in calcium such as dairy products will also reduce the magnesium content in the body.

　　Zhai Fengying told reporters that magnesium deficiency in Chinese is not very serious, which may be related to our eating more omnivores. However, young people who often eat fast food and potato chips should be more careful. Magnesium is very important for neurons that transmit signals to muscles, and it can also help the body to produce more melatonin and adjust people’s sleep patterns. Therefore, slight magnesium deficiency can lead to muscle spasm and insomnia. However, Wang Xingguo pointed out that there may be more muscle spasms caused by magnesium deficiency in Britain, but for Chinese, it is more related to calcium deficiency. Chen Xiafei said that severe magnesium deficiency can cause heart disease and gastrointestinal diseases. 　　

　　Magnesium-containing foods: corn, whole grain foods, preserved fruits, mushrooms and nuts. If you choose supplements, you should pay attention to avoiding dairy products and foods rich in calcium. 　　

　　Recommended daily dose: 300 mg in Britain and 350 mg in China. 300 mg is equivalent to 9 scoops and a half of corn flour, 240 grams of coarse grain noodles, 11 slices of whole wheat bread, 20 figs and 22 small walnuts (the best nut source of magnesium).

　　Urethral infection and long wound healing time.

　　Lack of vitamin C Wang Xingguo said that Westerners eat more meat and less vegetables, so it is easier to lack vitamin C; In China, most people who lack vitamin C are young people with irregular diets. Studies have shown that vitamin C can reduce the number of harmful bacteria in the urethra, and if it is lacking, it is easy to cause urethral infection.

　　It is also very important for the composition of collagen, the strength of skin tissue and wound healing. As long as trace amounts are lacking, there will soon be increased abrasions, frequent bruises and long wound healing time. Chen Xiafei also pointed out that severe vitamin C deficiency can lead to scurvy.

　　Foods containing vitamin C: citrus fruits, broccoli, red vegetables (tomatoes, red cabbage, etc.). 　　

　　Daily recommended amount: Vitamin C is a water-soluble vitamin, which cannot be stored by the body, so it needs to be supplemented every day. The recommended dosage in Britain is 60 mg, and that in China is 100 mg. 60 mg is equivalent to 2 kiwis and 8.5 spoonfuls of tomato juice. Duobuwei C will not cause harm to the body, because the excess will be excreted through urine.

　　Cold hands and feet and selenium deficiency

　　Selenium can regulate thyroid function, while thyroid secretes hormones, which control the metabolism and blood circulation of the body. People with slight selenium deficiency have poor blood circulation and feel cold hands and feet; Severe selenium deficiency leads to low immunity, decreased vision, and susceptibility to cardiovascular diseases and tumors. Selenium has a certain detoxification effect, which can combine with heavy metals in the body and reduce their harm.

　　Selenium-containing foods: shellfish and seafood are the best, and their selenium content is relatively stable.

　　Daily recommended amount: 75 micrograms for British men and 60 micrograms for women; China 50 micrograms. The recommended amount in Britain is equivalent to 1.5 tuna sandwiches and 175 grams of cod.

　　Dry and rough skin, vitamin A deficiency

　　Chen Xiafei pointed out that most people are slightly lacking in vitamin A, and few people are really seriously lacking. Vitamin A is famous for keeping the skin soft and elastic. Dry and rough skin, poor eyesight in dark light and repeated respiratory infections of children have a lot to do with it.　

　　Foods containing vitamin A: pork liver, eggs, dairy products, red and orange fruits and vegetables. 　　

　　Recommended daily dose: 0.8 mg in UK and 800 international units in China. It is equivalent to 100 grams of butter, 2 carrots, 3/4 red peppers and 3 cantaloupes.

　　Pre-menstrual stress zinc deficiency

　　Wang Xingguo said that the iron and zinc deficiency in Chinese is more serious than that in the west, which is related to the fact that we eat less seafood and meat. American studies have found that women’s zinc content is very low in the 13 days before menstruation, which leads to insufficient secretion of progesterone and endorphins, so their mood is very tense, anxious and painful. "Severe zinc deficiency will affect prostate health, or lead to children’s partial eclipse, eating soil and other pica." Chen Xiafei said. 　　

　　Zinc-containing foods: shellfish, meat, cashew nuts, coarse grains. 　　

　　Daily recommended dosage: 15 mg in the UK, 15 mg for men and 11.5 mg for women in China. It is equivalent to 3 oysters, 2 crabs and 272 grams of beef.

　　Fatigue, drowsiness and iron deficiency

　　The important component of hemoglobin that transports oxygen in blood is iron. Arens said that a little iron deficiency can make people feel tired, sleepy, lifeless and listless, and in severe cases, it can cause iron deficiency anemia. Wang Xingguo thinks that the iron deficiency in Chinese is more serious, which is related to the fact that we absorb more iron from plants. Spinach contains more iron, but the absorption rate is only 1%, which is far less than the iron supplemented by lean meat. 　

　　Iron-containing food: red meat is the best source, followed by egg yolk and preserved fruit. Vitamin C helps iron absorption, but tannic acid in tea hinders iron absorption. 　　

　　Daily recommended dosage: 14 mg in the UK, 15 mg for men and 20 mg for women in China. 14 mg is equivalent to 360 grams of coarse grain noodles, 51 preserved apricots and 2 boiled eggs.

　　Paralysis of hands and feet and potassium deficiency

　　Chen Xiafei told reporters that people who love salty food, love sweating and drink and smoke often lose potassium in their bodies. Potassium will affect nerve conduction. A slight deficiency will make people feel paralyzed and weak, and in severe cases, it will affect heart health. Potassium-containing foods: almonds, peanuts, lentils and asparagus. 　　

　　Recommended daily dose: 3500mg in Britain and 2000mg in China. 3500 mg is equivalent to 8.75 bananas, 31 preserved apricots and 7 baked tomatoes (baking reduces the moisture of tomatoes and increases the density of potassium). ▲ (Life Times reporter Zhang Jing)

Toyota Corolla’s impression of this car is: sturdy, durable and economical. On this basis, the dual-engine model has increased the advantages of softness and fuel saving, which can be said to be an improvement in performance. Now the new Corolla is built based on TNGA architecture, except for power and fuel consumption, the exterior interior has also been improved to some extent. Let’s analyze how this car is.

The new Corolla is more beautiful and fashionable than the old one. Although many people think it is not beautiful enough, the visual effect of the whole car is not bad, and the front and rear are very recognizable.

The interior is mainly eye-catching, decorated with chrome trim to enhance the sense of fashion; The 9-inch LCD dashboard (supporting voice control and car networking) enhances the sense of science and technology, but the 143,800 dual-engine elite version does not have a reversing radar, and the use of fabric seats and plastic steering wheels is not enough in terms of materials.

Compared with the models of Focus and Lei Ling, the reason for considering Focus is handling, but the old Focus 1.5T+6AT is much worse in terms of power and shift smoothness, and the 6AT transmission is not fuel-efficient. The main advantage of Corolla’s dual engine is fuel economy, such as commuting, turning on the air conditioner 23, and not turning on the ECO energy-saving mode. The fuel consumption per 100 kilometers is 3.8L/100km, and it shows that it can run 1000+km after being filled with oil, so the car cost is economical and applicable.

The reason why Corolla dual-engine saves fuel is that Atkins cycle engine, Ni-MH battery and permanent magnet synchronous motor are used. The motor can improve the driving performance of the vehicle by driving the vehicle and supplementing the engine power. In EV mode, the motor drives the vehicle independently; At medium speed, the MG1 engine is driven by the engine, and the MG2 motor charges the MG1 motor.

Corolla double engine uses high-voltage Ni-MH battery and 12V low-voltage battery, and realizes the conversion of alternating current and direct current through high-voltage distribution box, with the highest voltage reaching 600V V. The E-CVT transmission includes MG1 and MG2 motors, and the engine is connected with the planetary gear ring of the MG2 motor. When the gear position is in N gear, the engine is idling and will not drive the motor to generate electricity, so it is better to stop the gear position in D or P gear in a short time, and the D gear engine is in the closed state, which is more fuel-efficient; P gear can start and stop the hybrid system, which is safer.

In terms of car purchase price, the car purchase price of the 2021 Corolla Twin Engine Elite Edition in the 4S shop is 121,300 yuan, which can be discounted by 21,500-21,500 yuan, and the total car purchase cost is 133,500 yuan.

The problems needed in the later maintenance of this vehicle are as follows: (1) Pay attention to the need to use a special computer for data matching in brake fluid replacement and throttle cleaning, such as setting ECB cancellation mode when replacing brake fluid, canceling the vacuum generated by motor-driven vacuum pump, and then replacing brake fluid.

(2) Clean the vent for heat dissipation of HV battery. The low-voltage 12V battery is located on the right side of the trunk. When charging and discharging the battery, it needs to be ventilated and cooled by a blower. When using it, it needs to keep the vent clean and free from dust. As shown in the following figure, when powering the vehicle, the positive pole should be connected to the special terminal in the fuse box in the engine compartment, and the negative pole should be connected to the body ground to prevent excessive current.

To sum up, the overall car experience of the Corolla twin-engine is good, and the price of about 130,000 yuan is more cost-effective. Although the comfort and configuration of Corolla in the car are not outstanding enough, such as the motor noise when driving at low speed, the plastic feeling of the center console at your fingertips, halogen headlights, etc., Corolla is more competent from the aspects of family car and urban transportation. What do you think of this car?

Writing | Cheng Shushu

Editor | Li Xinma

Title map | IC Photo

Hengdian has become a "vertical shop"-a recent hot stalk, which is also the proof of the popularity of this year’s short play.

With ""oh! The Queen Mother came to work, and the user’s recharge broke through 12 million in 24 hours. After the flash marriage, Mr. Fu’s vest couldn’t be hidden, and the recharge broke through 20 million in one day. The news such as "Unparalleled" went online for 8 days, and the recharge broke through 100 million. The myth of the short program "Get rich in 10 days after filming in one week" has been spread on the Internet.

The spring breeze is not just blowing in the south of the Yangtze River. When miniseries swept the domestic market, many miniseries platforms also turned their attention to overseas markets, and started overseas "local flavor lovers" business through "cultural export". Recently, in particular, the regulatory policy of domestic mini-short plays has become increasingly strict, and going to sea has become a new continent that the clippers yearn for.

According to reports, ReelShort, a short drama product of Maple Leaf Interactive, a subsidiary of Chinese Online, earned a net income of $459,000, or 3.28 million yuan, on November 11th. As of November 17th, its accumulated net income has exceeded $22 million, or about 160 million yuan.

This kind of nugget ability even makes A shares do it one brace up. At the close of November 8, Chinese Online, Palm Reading Technology, Tianwei Video, Huanrui Century and other daily limit; On November 22nd, the short play interactive game board rose by 5.09%, Chinese online rose by more than 10%, and many stocks such as Tianwei Video, Zhongguang Natural Selection and Gravitation Media were daily limit. As of the close of November 24th, the market value of Chinese Online soared by 14.6 billion yuan in November.

Source: Oriental Fortune Network

The popular "short drama concept stocks" in the capital market and the rumor that "short dramas go out to sea and make millions of dollars a day" make short dramas go out to sea the most popular "split" in the content industry at the end of the year. Undoubtedly, this will attract a large influx of capital and practitioners. However, can every entrant get a share of this "window"?

01, "frolic in the waves"

Tracing the story of the short play going out to sea, I have to go back to two years ago.

At the end of 2021, Youku began to try to develop and launch overseas short plays. In the same year, Aauto Quicker’s overseas version of Kwai also launched Telekwai, a brand of short plays. In addition, Tencent Video and iQiyi have gradually increased their investment in overseas markets and released some short plays. On the international version of "Youaiteng" App, YouTube and TikTok accounts, there are channels dedicated to short plays.

However, these pioneers are not today’s "trendsetters".

When it comes to the head players of the current short play, the ReelShort mentioned above is the first one that comes to mind. After it was officially launched in August 2022, it mainly focused on the North American market. The previous short play "Fated To My Forbidden Alpha", which was very popular overseas, came from this platform.

According to the data of SensorTower, in July this year, the total downloads of ReelShort on GooglePlay and App Store reached 1.9 million times, and the monthly flow reached 6 million dollars, which was almost the same as Netflix’s monthly income. In November, it became the head player of the current short play sailing track, and even surpassed TikTok during the "Double Eleven" period, becoming the most popular entertainment application in the Apple Store in the United States.

The overseas short drama platform that is in the limelight also has GoodShort, a subsidiary of New Reading Times, but it was launched almost a year later than Reelshort. GoodShort mainly focuses on the European, American and Korean markets, and its development path is similar to ReelShort’s. In the early days, it mainly translated domestic short plays and put them online, and then used the local team to prepare for shooting.

Flex TV, which was launched by Anyue Technology in October 2022, occupies a certain position in South Asia. Since its launch more than a year ago, Flex TV has been downloaded in Thailand’s Top50 list. According to Sensor Tower data, in July 2023, the total download volume of FlexTV on Google Play and AppStore was about 160,000, and the total monthly flow was about 500,000 US dollars.

DramaBox launched by Dianzhong Technology in April this year, 99TV and Short TV launched by Kyushu Culture in the second half of this year, MoboReels launched by Changyou Technology in July this year and Mini Episode launched by Chizicheng Technology also have certain influence.

It is not difficult to find that in this wave of sea-going competition, the head players who are rapidly emerging, such as Chinese Online, Anyue Technology and New Reading Times, have a deep foundation in the sea-going market, and their huge net-text reserves have become an important source of short drama scripts.

For example, Maple Leaf Interactive has two novel products, Kiss and Chapters, which are currently in the first echelon of American interactive novels; Anyue Technology’s overseas online reading App covers 10 languages and has accumulated 10 million users; The new reading era has many overseas novel apps such as GoodNovel, GoodFM, BueNovela and MegaNovel.

The other category is short drama production companies such as Kyushu Culture and Dianzhong Technology, both of which are the head companies of domestic small drama tracks.

02, play each are not identical.

Oranges are orange in Huainan and bitter orange in Huaibei. The same is true for short plays. After going out to sea, the audience and business model have changed compared with those in China.

Previously, DoNews learned from the writers of domestic small program short plays that domestic small program short plays are more likely to explode on male frequency, and they are mainly aimed at security guards, courier brothers and takeaways. Different from the domestic small program drama, the main audience is the sinking market users. In the European and American markets, the middle class is the main force to consume short dramas, and female frequency is more popular. According to Shen Xiang, Leon, an overseas short drama practitioner, the "Bao Ma clan" between the ages of 25 and 45 is the core audience in the European and American markets.

Different audiences also affect popular themes. According to June, senior operation manager of Yeahmobi social media marketing, short drama audiences in European and American markets prefer themes with traditional European and American images, such as werewolves, vampires, giants and fantasy. However, the popular domestic themes such as "my husband" and "God of War" are "not available" overseas.

In terms of business model, domestic and overseas products are fundamentally different. Domestic short-play products are short plays, while short-play products after going out to sea are actually short-play apps launched by major manufacturers.

Image source: APP Growing

Short plays sold on the "one-off" platform of small programs allow users to spend money on dramas. When products become apps, there are more possibilities for commercialization. Take Reelshort as an example, there are two ways to watch advertisements and pay for it. There are 60 episodes of "Fated to My Forbidden Alpha", which are charged from the second episode, and each episode is unlocked with 66 gold coins (equivalent to RMB 5 yuan). If you don’t want to spend money, you can also watch the advertisement unlock, but the number of views is limited. In addition, like Goodshort, there are subscription systems, rewards and business cooperation.

The product has changed from short play to App, and the goal of producers has also changed from how to make short play content capture users to how to make App retain users.

It is understood that short plays are currently divided into two forms: the first is to translate the original domestic videos and upload them to applications or third-party video platforms, that is, to translate dramas; The second is to build a local team and invite local actors to shoot short plays that are more suitable for local users according to the script.

However, now there is a short drama filmed in the sea with AI, that is, a domestic short drama is changed into an overseas "face" through AI face change+language/mouth change. It is said that the cost of a short drama is 600,000 yuan, but it has not changed the essence of the plot, which can only be regarded as a more advanced translated drama.

According to June’s analysis, the translated drama can achieve a rapid start-up, with a large number of new products in a short period of time, and the initial investment cost is less. However, due to different regions, cultures and preferences, the content may not be accepted by local users and it is not easy to explode. Building a customized drama with local cast is conducive to quickly breaking the circle and forming a certain user pool, but the cost of initial investment is large, and the period of shooting, editing and post-adjustment is long, which leads to a relatively slow pace of new entry.

Comparatively speaking, it is certainly more attractive for users to build customized dramas with local teams, but if the frequency of updating is too slow, it will affect users’ retention. But to maintain a certain frequency of new access, the investment in funds will certainly not be less.

03, a steady profit, or a big risk?

Although the market prospect seems broad, not all entrants can easily "nugget".

After deeply understanding the domestic paid short drama industry chain, we will find that the success of small program short drama does not mean that it is an easy business to make money. Short plays with a daily recharge of 10 million yuan are rare, and the box office of over 100 million yuan is even rare. Coupled with the high investment cost, it limits the profitability of the overall market of short plays with small programs.

According to the calculation of Wang Xiaoshu, the founder of Jiashu Technology, "About 0.8-0.9 yuan will be used to pay for advertising in the box office of 1 yuan miniseries. Producers usually only get about 0.1-0.15 yuan, and the box office of 10 million really gets more than one million, and it also covers hundreds of thousands of shooting costs. The cost of casting flow is high, but the explosion rate is not high. In a year, there is only one "Warriors", which is less than 10%, which means that only 10% of the dramas can be returned, and 90% of the dramas will lose money. "

Short plays are also facing the same problem when they go out to sea. Currently, the active revenue data in the market come from head platforms such as ReelShort and GoodShort, and there are still too many unknown data in the overall market to be verified.

Furthermore, according to June, the head App will also be launched in Ins, Facebook, YouTube, TikTok and other channels and diverted to the App Store. In other words, it is also very important to choose a localized social media platform for streaming. The person in charge of Jiashu Technology has recently publicly stated that unlike domestic streaming, a drama is released overseas through Google and Facebook, with a long cycle and a slow start. This may lead to a relatively slow return of funds for short plays at sea.

In addition, although domestic short plays are under supervision, they have to face the problem of whether the content is compliant, but overseas, copyright issues also need to be considered. If a piece of background music is found to be infringing, it will result in a fine or even the entire App being removed.

Finally, the market, different from the domestic mini-drama, which developed from HarmonyOS, is controlled by the online company or the head company in the field of short drama production, which also increases the difficulty for latecomers to stand out.

The short play going out to sea is a good commercial exploration of the domestic short play industry, but there are many differences between overseas and domestic in terms of production process, operation logic and even market environment. Although the myth of making wealth is flying all over the sky, if you really want to enter the game, you should be cautious again.

1905 movie network news Take movies as a bridge and aesthetics as a way.Return to the film itself and witness the power of criticism.《Today shadowcriticize"Specially planned" Watching Movies ",50 hot films in the past five years x 50 professional film critics,An in-depth film appreciation class,A test of the strength of film critics.

Before the start of the year, if you ask the old editors what they expect from China movies in 2020, the answer is no doubt — — "Seal the universe".

In the summer of 2019, an animated film (hereinafter referred to as "Nezha") won 5.013 billion yuan at the box office by word of mouth, becoming the first animated film to top the box office in China.

Considering the determination of the following "deification" theme projects, professional film media, including Today Film Review, have predicted that Nezha will be the prelude to "deification universe" in 2020.

Unfortunately, affected by the epidemic, Legend of Deification became the first film to quit the Spring Festival. It is not known whether the first part of the trilogy of deities, which is scheduled to be released in the summer, can be released as scheduled.

However, while waiting for the "universe of deities" to take shape, Sha Dan, the curator of China Film Archive, who is a guest of "Watching the Movie", as a film history researcher and film critic, has freshly cracked the "heaven" big villain mystery of "Nezha".

Today’s film review: the antagonistic relationship in Ne Zha

Emotional opposition bred by Tai Chi Yin and Yang

For most China audiences, it is not easy to make a decision to go to the cinema to watch domestic animation.

On the road of "Nezha" to the top box office of Chinese movies in 2019, it has a solid accumulation of "Guo Man" films that have been well-received by people in recent years.

In addition to the "burning" texture that has been rapidly improved in animation technology, the content arrangement of these "Guo Man" works, which is most talked about by the audience, still lies in the great integration of the essence of traditional culture and the spirit of the new era.

"Everyone says that this movie is particularly popular, but from a professional point of view, (it can succeed) is not a burning problem, and there are very strong skills." From a professional perspective, the outstanding impression that Nezha brought to Shadan originated from the antagonistic relationship between the concepts of Yin and Yang.

“The aura of heaven and earth, after the year before last, gave birth to a mixed pearl … …"Do you remember whose tone this sentence appeared at the beginning of the film?

He is a potbellied, trumping Taiyi real person. At the same time, he is also the point of view of the whole film.

"Taiyi is a Taoist, and Taoism has a very important Tai Chi symbol." Digging deep into the essence of viewpoint, Shadan found the key to the narrative structure and character composition of Nezha — — The antagonistic relationship between Yin and Yang in Taiji.

From the narrow perspective of film language, Shadan introduced a film term (knowledge point): the opposition between sound and painting.

Sound is contrary to the content of the picture, that is, sound is not an accessory or supplement to the picture, but excavates the inner activities of the characters from the opposite direction, or creates some emotions and hints some thoughts. The opposition between sound and painting has produced a new appearance and formed a new quality.

In Nezha’s innumerable opposites between sound and painting, Shadan chose two typical paragraphs in which Nezha started from joy but fell into sadness.

First, it is a scene in which little Nezha tries to play with other children in Chentangguan.

Looking at the children playing hide-and-seek in the streets, Nezha in babbling spread out his arms and planned to join them, but he didn’t want to be thrown into the mud by the older children who just thought he was a "magic boy". The innocent smile on the immature face is in sharp contrast with the vicious words around "the monster gets out of Chentangguan".

Secondly, it was Nezha’s third birthday party that Excavate "forced" all the people to attend when he learned that Aiko was dying soon.

Persuaded by his parents, Nezha finally smiled and went to the birthday party happily. But at the same time, people who have always been afraid of Nezha’s stubbornness are hard to smile, and musicians even play funeral music on this big occasion.

It is the strong emotional contrast that leads to the more tragic fate collision of the film theme.

The real "villain" who makes twin heroes

Compared with the original "Romance of the Gods", the biggest subversion of Nezha lies in the ingenious adaptation of Nezha and Ao Bing.

In Shadan’s view, Nezha and Ao Bing are actually the "double protagonists" of the film. "This kind of dual protagonist form is called the’ twin hero’ narrative style in the history of movies."

The term "twin" is materialized in Nezha by the concept of the opposition of Yin and Yang. "(Nezha and Ao Bing) One is the magic bead, and the other is the spirit bead, because the spirit bead itself is confused, which makes their respective emotions and humanity have a very twisted place."

What makes Shadan feel "twisted" is the huge collision between their completely different surfaces and their coincidences. Nezha’s keynote is sunny land red, while Aobing’s background is blue and depressing deep sea blue. However, hatred between different races has melted into heroic brotherhood in the warm scene of kicking shuttlecock on the sunset beach.

Analyzing the source of opposition in this theme, Shadan thinks of the "heaven" in the shocking sentence "I am not determined by heaven" instead of the obvious villain Shen Gongbao who plays a role in provoking the relationship between them.

"Who is’ God’?" In his view, there is a bigger "dangerous person" behind the fight between Nezha and Ao Bing, the incarnation of the White Dragon. "It is the God of the Yuan Dynasty, because of his reasons, Nezha and Ao Bing are doomed."

Distributing the wrong spirit beads and magic beads by Taiyi’s hand comes from the lofty and exaggerated "immortal" in the film — — Yuan Shi Tian Zun

In Shadan’s eyes, the image of Yuan Shi Tian Zun in the film represents an old and outdated attitude, and it is the director’s fiercest critical emotion that he closes the door at the critical moment of survival and does not see the bridge between Taiyi and Li Jing.

"In fact, the biggest villain, I don’t think it’s Shen Gongbao, but Yuanshi Tianzun, who made an established routine for everyone." Nezha, who didn’t give in to fate, rebelled against the ancient Buddha.

Liang Yang correspondent Yuan Jiaxin, who is doing nucleic acid testing.

　　Changjiang Daily News (Reporter Liu Xuan correspondent Yuan Jiaxin) Liang Yang and Li Jin, who just finished their wedding on January 12th, originally planned to take a honeymoon trip, but their plans were disrupted by the sudden epidemic. From the beginning of the epidemic, they, both laboratory doctors, have been at the forefront of the fight against the epidemic. "The work is very hard and dangerous. There is only one belief that supports us: complete the test as soon as possible and let the patients receive treatment earlier." On February 16th, the newlyweds said in an interview that when the epidemic ended and Wuhan returned to prosperity, they would make up their honeymoon trip.

　　Liang Yang is a laboratory doctor at Wuchang Hospital in Wuhan, and her husband is Li Jin, a doctor at Zhongnan Hospital of Wuhan University. On January 21, Liang Yang received a notice that his hospital became the second wholesale hot-spot hospital. The two men decisively returned their air tickets, gave up their vacations, and returned to the hospital to stick to their posts.

　　At that time, the fever clinic of Wuchang Hospital was crowded with patients who came to see a doctor every day. Due to the shortage of nucleic acid kits, patients waiting for the diagnosis of nucleic acid testing line up. Looking at the crumpled laboratory sheets in patients’ hands, Liang Yang and her colleagues looked in their eyes and were anxious.

　　On January 27th, Wuchang Hospital became the second batch of designated nucleic acid detection hospitals. Under the guidance of Wuhan CDC and the support of Air Force Medical Team, the clinical laboratory began to do nucleic acid detection. "I was really scared at first. I had to face novel coronavirus who didn’t know enough every day. I didn’t know under what circumstances I would be infected. It was a battlefield on the scalp."

　　As the backbone of the laboratory, Liang Yang needs to do at least 200 cases every day, and at most, he has completed 253 cases a day. Working continuously for nearly 7 hours every day, drinking water is a luxury. Wearing protective clothing for 4 hours will lead to hypoxia, and wearing gloves for a long time will make Liang Yang’s hands covered with red rashes.

　　"These can also endure, the most afraid of is the body suddenly uncomfortable. Once I had a high fever and a cough, I asked him ‘ What if I get infected? ’ He said, ‘ If you are infected, we will be isolated at home together, and we are not afraid. ’” Speaking of the husband who has been encouraging himself behind his back, Liang Yang instantly became red-eyed. Fortunately, the later inspection results were all normal. Colleagues laughed and called them "drug-playing couples". "Yeah, we deal with such a powerful virus every day." Liang Yang explained with a smile.

　　Without much gossip, go straight to the topic ~

　　The eleventh pass first met Tianmen array

　　One-on-one hit: none

　　Dialogue: ① Yang Yanzhao-Yeluxidi

　　(2) Yang Yanzhao-Yale blame.

　　(3) Yang Yanzhao-Yelvchenko

　　(4) Yang Yanzhao-Yale studies ancient times.

　　Reward: [Pass Award-Dragon Scale+Seal] Pay attention to a lot of archiving. Benguan is a small Jiugong array. At first, all our troops entered the array. When our whole army entered the array, the array gate was closed.

　　Note: the ambush will kill the enemy generals first, because the generals will not die, and the soldiers will be resurrected.

　　Here, the number on the table is used instead of the nine palaces.

　　Our army entered gates 4 and 8.

　　Our army entered gate 8 and gate 1 opened. At the same time, four ambushes in the Yale-Xidi belt appeared in 2.

　　When our army entered the 2 nd and 5 th gates, at the same time, four ambushes appeared in 6 th.

　　When our army entered 6, (only one square in front of the door when entering, otherwise all of us would be in chaos, forbidden to curse and settle down) 9 doors opened, and Ye Lvxie led four ambushes to appear in 9,

　　When our army enters 9, (enter only one square in front of the door, otherwise all will be in chaos, forbid the curse and settle down) 3 doors will be opened. The last wave of enemy ambush appeared in

　　Killing all the ambush will eventually trigger the plot → The enemy will resurrect a person in every door. At the same time, there will be a 61-level friendly God of War Qilang with a dragon gun and a God of War ring outside the upper phalanx. Although invincible! But it’s useless, and we can’t get into the array, and in the end, we have to completely destroy the enemy before we can pass.

　　Note: this level has been changed for several weeks, and the enemy soldiers appear directly. Carmen just does it. It’s a simple level.

　　Plot opening great meritorious service shop

　　The Battle of Mukezhai in the 12th Pass

　　One-on-one: Mu Guiying Yang Zongbao (caught)

　　Mu Guiying-Jiao Zan

　　Mu Guiying-Meng Liang

　　Dialogue: None

　　Reward: [repel Mu Guiying once-flying dragon cloak]

　　At the beginning of this pass, our large forces went to the designated place together.

　　When any one of our troops, Jiao Zan or Meng Liang, went to the middle of the wasteland above, he triggered an ambush to attract the attention of the ambush to wear silver armor. This wave of ambush wasteland is infinite in Shan Lan, and the forest is infinite in cursing, which is very annoying. (Mugua will be killed last, or he will be resurrected indefinitely)

　　After clearing the ambush, Mu Guiying appeared at the top left.

　　Just wait for her in the wasteland. Don’t go there. Mu Guiying ares wasteland is only 100% terrain-adaptive, and female soldiers are 90%. The sooner you trigger Mu Guiying’s two one-on-one fights, the better, because Mu Guiying’s department including Mu Guiying will be resurrected indefinitely. Hey, I’m so angry.

　　After triggering Mu Guiying’s two one-on-one fights, the plot prompts Jiao Zan and Meng Liang to retreat to the designated place below and run quickly.

　　When they arrived at the designated place, Yang Zongbao appeared.

　　Two 2b’s followed Yang Zongbao to find a place in Mu Guiying, but Yang Zongbao beat Mu Guiying one-on-one and the plot was caught. At this time, the plot gives a hint that the two 2b have to retreat to the designated place below, and there are also nine thieves and soldiers blocking the road.

　　Finally, Jiao Zan and Meng Liang arrived at the designated place for customs clearance.

　　Note: This level has been changed for several weeks. Just do it directly. The enemy will not be resurrected. Mu Guiying will be resurrected once. It is a simple level. At first, only the enemy sprayers, martial artists and a Feng Shui master went down, and a counselor would come down and dry them up, then Gong Bing and Bow Ride, and then the bear trainer. Finally, destroy the remaining troops and pass easily.

　　R story Yang Yanshun (Feng Shui Master) joins in.

　　The thirteenth pass will fight Tianmen array again.

　　One-on-one: Yang Yanzhao-Bai Tianlong

　　Yang Zongbao-Bai Tianlong

　　Wang Gui-Taurus (Death)

　　Dialogue: None

　　Reward: [Wang Gui heads-on earth Taurus-Iron Helmet, none of us retreats-Meng De’s new book]

　　This level is a broken array level.

　　At the beginning, our army went up. When our whole army crossed the intersection, the enemy appeared.

　　After destroying the enemy, the next round changed ranks and an ambush appeared. At the same time, our defense is lowered.

　　After destroying the ambush again, we will change the formation again in the next round, and there will be an ambush again. At the same time, our attack and morale will be reduced.

　　After eliminating this wave of ambush, it’s time for Mu Guiying’s solo performance. Finally, five Liao army generals appeared, all of whom were wiped out.

　　Note:

　　In the third round, our army was paralyzed.

　　In the sixth round, our army banned the curse.

　　In the ninth round, our army was paralyzed and poisoned.

　　The twelfth round, our army paralysis+poisoning.

　　In the fifteenth round, our army cursed+poisoned.

　　R Plot Mu Guiying (God of War) and Yang Zongyuan (Tiger Riding with Yang Men) join in.

　　Note: From this level, the following four levels triggered any one-on-one confrontation and dialogue about Yang Zongyuan, and he would die.

　　Plot opening great meritorious service shop

　　The 14th Gate of the Great Sky-Breaking Gate Array

　　One-on-one hit: none

　　Dialogue: Yang Zongyuan-Yale studies the ancient times

　　Yang Zongyuan-Yelu Xidi

　　Yang Zongyuan-Yelusha

　　Yang Zongyuan-Xiao Tianzuo

　　Yang Zongyuan-Xiao Tianyou

　　Yang Zongyuan-Brother Yelvxiuge

　　(Make sure Yang Zongyuan’s attention doesn’t trigger the dialogue)

　　Reward: [Pass Award-No Arrow, Dark Iron Sword]

　　At the beginning of the plot, Liulang died, and Zongbao inherited Liulang’s ability and learned to rise in stunts.

　　Kill all the enemies under the high week, and then the enemies will appear in the east, just destroy them all. It’s a simple pass.

　　The plot obtained Yang Yanzhao’s relic-Hummer (auxiliary explosive power 15%).

　　The plot Yang Yande (Boxing Saint) brings his own gossip stick (counterattack after counterattack) to join.

　　Plot opening small meritorious service shop

　　The fifteenth level of the big skyshatter gate array II

　　One-on-one: Yang Zongyuan-Xiao Tianzuo (dead)

　　Yang Zongyuan-Yelv blamed (died)

　　Yang Yande-Xiao Tianzuo (death)

　　Dialogue: Yang Zongbao-Yelusha

　　Yang Yanshun-the sorcerer Yelu Haonan

　　Mu Guiying-The God of War Yelu Haonan

　　(Make sure Yang Zongyuan’s memory doesn’t trigger dialogue and one-on-one hit. There is a lot of dialogue, so I won’t write it here)

　　Reward: [Triggering Yelu Haonan’s dialogue and one-on-one hit-banana fan, Yang Yande’s one-on-one hit Xiao Tianzuo-Qingnangshu]

　　Broken array prompt:

　　Simon: repel Yerusha when there are 7 people left.

　　North Gate: When the remaining 7 people repel Yeluxidi, and finally kill Xiao Tianyou.

　　East Gate: Kill 4 generals first, and then kill the small soldiers (note that the generals in East Gate will return to their original positions with blood below 100).

　　South Gate: Kill the soldier first, then the general (you can trigger the one-on-one fight to kill the general first, without affecting the broken array. )

　　Middle Array: Kill the sorcerer Yelu Haonan first, or the soldier will be resurrected. Kill the soldier after Yelu Haonan dies, and finally kill the god of war Yelu Haonan, or the god of war Yelu Haonan will be resurrected.

　　At the beginning, all our troops added attack and defense and played according to the tips of breaking the array.

　　Pay attention to break the array of each door, don’t rush in, or there will be four ambushes in the four corners of Yeluhao South Central Array, and our army outside the Central Array will be in chaos. Therefore, after the array of each door is broken, all the people in this door stand in the intersection and wait, and after the other doors are broken, all enter the intersection and wait. In the next round, when our army is all operational, we will trigger the ambush.

　　I remember that Yang Yanshun talked to Yelu Haonan, the magician, and after killing Yelu Haonan, he would become Yelu Haonan, the god of war, which finally triggered Mu Guiying’s dialogue and killed him.

　　Plot opening great meritorious service shop

　　The Battle of Liangmen Pass in the Sixteenth Pass

　　One-on-one: Yang Zongyuan-Xiao Tianyou (retired)

　　Yang Yande-Xiao Tianyou (retired)

　　Dialogue: Yang Zongbao-Mysterious Military Commander

　　Yang Zongyuan-Yelusha

　　Yang Zongyuan-Brother Yelvxiuge

　　Yang Zongyuan-Yale studies ancient times

　　(Make sure Yang Zongyuan’s attention doesn’t trigger dialogue and one-on-one hit)

　　Reward: (Triggering the dialogue between Yang Zongbao and the mysterious military commander, getting through the customs-golden cupping gun)

　　This is a bit difficult, only 20 rounds, and our army will attack the city as soon as possible. It is suggested to attack the east side, and enemy reinforcements will appear behind the south side. The seduction tactics of this pass are useless, so we can only fight hard, and make good use of our personnel skills such as return, cursing, encouragement, great awakening and so on. If you can’t attack the city in six rounds, you will know what is difficult to fight. (Note: AI is defective. If our personnel are not confused or paralyzed at the end of action, when the enemy is in action, the mage will all use confusion or paralysis or ability reduction skills, so making good use of Great Awakening is the key to pass this level.)

　　In the sixth round, the mysterious military commander of the enemy reinforcements appeared behind the South City with four rides and four bows, while Lin Xiao took three thieves and three tiger trainers and Zhao Yangqian took three thieves and three bear trainers on both sides of the upper left corner. At the same time, all the enemy troops attacked. Our army stood by the city and wiped out the enemy.

　　Pay attention to Lin Xiao and Zhao Yangqian. These guys are God of War, and they have extremely high offensive and defensive abilities. But their spirit is low, and they all have an extra 15% damage from spells.

　　The 17th Pass: The Pacification War of Liao State

　　One-on-one: Yue Sheng-Lin Xiao

　　Dialogue: Yang Zongbao-Yelusha

　　Yang Zongyuan-Yelusha

　　Yang Zongyuan-Xiao Taihou (death)

　　(Keep Yang Zongyuan’s attention and don’t let him talk. )

　　Reward: [Kill Brother Yelvxiuge-black silk scarf, Kill Ancient Yelvxuexue-White feather fan, Kill Jade Mirror-Bean Bag, Pass the Customs Award-Taiping Yaoshu]

　　This pass is an siege war, and our army is divided into two parts, each attacking one side. Because the two sides are not connected with each other, we should arrange our staffing on both sides reasonably. Don’t rush into the city after killing the two infantry who blocked the door. When our army is operational in the next round, we will send one person to lead out the ambush, and others will give priority to killing the strategists who pose a great threat to our army. The ambush is three on one side and three on both sides, both sides are the same.

　　After clearing the enemy, our personnel on both sides continued to move downwards. When you walk to the fence, stand in position, and wait for the next round of action, and also send one person to lead out the ambush. Both sides are the same.

　　After clearing the enemy, our personnel on both sides attacked the troops on both sides of the door. After clearing the troops blocking the door on both sides, when our personnel meet to kill the two fighters blocking the last door, there is still the last wave of ambush on both sides of our army and behind the dead fighters, so pay attention to wait until the next round of action to kill the last fighters.

　　Finally kill Xiao Taihou. Xiao Taihou must be killed last, or he will be resurrected indefinitely.

　　The 18th Pass Xiongzhou Guard War

　　One-on-one hit: Yang Zongyuan-Yin Qi (death) (all the enemy is in chaos+surrender, explosion)

　　Meng Liang-Jiangjiao

　　Dialogue: Yue Sheng-Lin Xiao

　　Jiao Zan-Hu Tianzhang

　　Reward: [No one retreats at this level. R The plot is won-your legend]

　　This pass is a city defense, and there is nothing to say. Make good use of our military skills.

　　In the fifth round, enemy reinforcements Lin Xiao and Zhao Yangqian each appeared up and down with three bows and two tactics and attacked both sides of our army.

　　Triggering Yang Zongyuan and Yin Qi’s one-on-one fight as soon as possible will make this pass a lot easier and finally wipe out the enemy.

　　The plot opens a small meritorious service shop.

　　The 19th Pass Xiongzhou Retreates the Enemy

　　One-on-one hit: none

　　Dialogue: Mu Guiying-Jiang Drink (attack drops)

　　Yang Zongbao-Jiang He

　　Reward: [Destroy the enemy completely-White Tiger and Baoyu]

　　At the beginning of this pass, we moved down and waited for the enemy to fight for the first time. Because the enemy didn’t have a counselor for the first time, Yang Yanshun and eight sisters and nine sisters could go up there to help Mu Guiying. Mu Guiying had better chop people every round, so that the enemy counselor can add blood to the enemy to prevent the output. Yang Yanshun adds blood or relieves Mu Guiying, and eight sisters and nine sisters export enemy counselors or just hit the nearest one.

　　In the fifth round, the enemy attacked in the second array (all bow and ride), and played the same way. Lin Xiao and Zhao Yangqian will return to the enemy Zhongjun after being repelled.

　　In the 10th round, all the enemies attacked. You can’t beat it. Find a chance to kill Jiang. Or set up a formation, fight and retreat, and retreat to the lower right corner of the city to fight back.

　　Finally, kill Jiang and drink or completely destroy the enemy.

　　Plot opening great meritorious service shop

　　The 20th Pass Snowfield War

　　One-on-one hit: Yang Zongyuan (attack and explosion reduction)-Zhang Rong (attack and defense reduction)

　　Yang Zongbao-Ginger Drink (Returned)

　　Dialogue: None

　　Reward: [Triggering Yang Zongyuan’s One-on-One Fight-He Ting and Zhuge Jin]

　　note:

　　1. Several of the enemy’s well-known people have no plan (taking 15% extra spell damage) stunts. Although the attack and defense are extremely high, they are quite easy to solve.

　　2. The first order of AI instruction of enemy counselor should be adding blood. Therefore, whether it is this level or the next big battle level, priority should be given to using range skill damage, or penetrating guns, bows, etc. Action instructions involving enemy planners.

　　In the first round, all our troops went up, but not too much. Enemy mentally retarded counselors will rush up and expose themselves to our attack range, and kill them first.

　　To get rid of the enemy vanguard, we can consider whether to play defense or attack. Remember to trigger Yang Zongyuan’s one-on-one hit.

　　In the tenth round, Lin Xiao, an enemy reinforcement, led three riders, four thieves, three tactics and four cannons to appear at the lower right, and Zhao Yangqian led four thieves, four riders, three cannons and four tactics to appear at the upper left.

　　When the remaining troops of our army are less than seven, it can trigger a one-on-one fight between Yang Zongbao and Jiang Drink, and Jiang Drink retreats. Our army’s overall offensive and defensive capabilities have increased, while the enemy’s overall capabilities have decreased.

　　Finally, completely destroy the enemy and pass through.

CCTV News:On March 30th, the website of the National Health Insurance Bureau exposed 10 typical cases of illegal use of medical insurance funds by designated retail pharmacies. It involves the settlement of medical insurance expenses for non-medical insurance designated retail pharmacies, the exchange of drugs and health care products outside the medical insurance catalogue with drugs in the medical insurance catalogue for settlement, the issuance of false drug purchase documents to cash back the insured, and the inconsistency of drug purchase, sale and storage data. The above-mentioned illegal acts caused the loss of medical insurance fund and harmed the vital interests of the majority of insured people. Designated retail pharmacies should strictly abide by the relevant laws, regulations and rules of medical insurance. The medical security department should crack down on illegal activities such as fraudulent insurance in designated retail pharmacies through daily supervision, on-site inspection, intelligent monitoring and big data analysis in accordance with the law, improve the efficiency of the use of medical insurance funds, and better protect the rights and interests of the majority of insured personnel.

1. Case of illegal use of medical insurance fund by Inner Mongolia Ruichen Pharmaceutical Co., Ltd. in Hohhot, Inner Mongolia Autonomous Region

In August 2021, the Medical Security Bureau of Hohhot City, Inner Mongolia Autonomous Region received a report clue, reflecting that Inner Mongolia Ruichen Pharmaceutical Co., Ltd. was suspected of illegally using the medical insurance fund. By collecting the sales records from January to July, 2021 and the data uploaded by the medical insurance system, the inspectors found that some drugs (such as Erding Granules, Huangqijing Granules, Shiquan Dabu Ointment, Qihu Hawthorn Granules, etc.) in the pharmacy were inconsistent in purchase, sale and storage, and the medical insurance fund was overcharged by 23,004.50 yuan. According to the "Regulations on the Supervision and Administration of the Use of Medical Insurance Funds", the results of the local medical insurance department are as follows: 1. Recover the medical insurance funds illegally used by the pharmacy and impose a fine of 2 times the illegal amount; 2. Interview the person in charge of the pharmacy and order it to be rectified within a time limit, and make irregular return visits to check the rectification of the pharmacy to ensure that the rectification is implemented. At present, the lost medical insurance fund of 23,004.50 yuan has been fully recovered, and the administrative fine of 46,009.00 yuan has been fully paid.

2. The case of illegal use of medical insurance fund by Tiedong Branch of Chengxin Yonghong Pharmacy Chain Co., Ltd. in Siping City, Jilin Province

In February, 2021, the Medical Insurance Bureau of Siping City, Jilin Province received the "Audit Transfer Handling Letter of the Audit Office of Jilin Province on the Issue of Taking Medical Insurance Fund from Tiedong Branch of Siping Chengxin Yonghong Pharmacy Chain Co., Ltd.", and the Siping Medical Insurance Bureau and Siping Audit Bureau formed a joint investigation team to seriously investigate and verify the situation reflected in the transfer handling letter. After investigation, there were some problems in the pharmacy, such as the untimely maintenance of drugs in the medical insurance catalogue and the replacement of drugs outside the medical insurance catalogue with drugs in the catalogue, resulting in the loss of medical insurance fund of 147,044.32 yuan. According to the Service Agreement of Designated Drugstore of Jilin Province’s Basic Medical Insurance in 2020, the local medical insurance department handled the following results: 1. Recover the loss of medical insurance fund caused by the pharmacy, refuse to pay all the deposit and reserve fund of the pharmacy of 882,343.09 yuan, and refuse to pay all the unsettled medical insurance fund of 794,973.05 yuan; 2. Dissolve the medical insurance service agreement of the pharmacy, and you may not apply for medical insurance within three years. At present, the lost medical insurance fund of 147,044.32 yuan has been fully recovered.

3. The case of illegal use of medical insurance fund by Huolong Store of Nantong Jianghai Pharmacy Chain Co., Ltd., Nantong City, Jiangsu Province

In March 2022, the Medical Security Bureau of Haimen District, Nantong City, Jiangsu Province discovered through remote video surveillance that there was a violation of the rules of drug exchange in the Cargo Long Store of Nantong Jianghai Pharmacy Chain Co., Ltd. Upon verification, the Cargo Long Store of Nantong Jianghai Pharmacy Chain Co., Ltd. has empty medical insurance cards to withdraw cash, swiping medical insurance cards for non-designated pharmacies, dispensing medicines with people’s certificates and other acts in violation of medical insurance regulations, involving the illegal use of medical insurance funds of 13,564.58 yuan. According to the Service Agreement of Nantong Basic Medical Insurance Designated Retail Pharmacy, the local medical insurance department handled the following results: 1. Recover the medical insurance fund illegally used by the pharmacy of 13,564.58 yuan, and deduct the penalty of 35,000.00 yuan; 2. Dissolve the medical insurance service agreement of the pharmacy, and you may not apply for medical insurance within three years; 3. Deduct 40 points from the institutional credit score of the pharmacy in 2022. At present, the lost medical insurance fund of 13,564.58 yuan and the liquidated damages of 35,000.00 yuan have all been recovered.

4. The case of illegal use of medical insurance fund by Shengde Pharmacy in Xinyu City, Jiangxi Province

In March, 2022, Xinyu Medical Security Bureau of Jiangxi Province and the Municipal Market Supervision Administration conducted an on-site inspection of the use of medical insurance funds by 30 designated retail pharmacies in the city from January, 2020 to November, 2021, and found that Xinyu Shengde Pharmacy was suspected of illegally using medical insurance funds. After verification, the pharmacy has the following violations: (1) brushing medical insurance cards for non-medical insurance designated pharmacies; Incorporate Chinese herbal pieces that cannot be paid by single taste into the medical insurance fund for settlement; The actual sales quantity of some drugs is less than the medical insurance bookkeeping quantity; Swap drugs and health care products outside the medical insurance catalogue into drugs in the medical insurance catalogue for settlement; Illegal settlement is limited to illegal activities such as the use of drugs for work-related injuries. The above acts involved illegal use of the medical insurance fund of 47,570.40 yuan. According to the Regulations on the Supervision and Administration of the Use of Medical Insurance Funds, the Detailed Rules for the Implementation of the Administrative Punishment Discretion in the Supervision of Medical Insurance Funds in Jiangxi Province (for Trial Implementation) and the Service Agreement of Designated Retail Drugstore of Medical Insurance in Xinyu City, the results of the local medical insurance department are as follows: 1. Recover the medical insurance funds illegally used by the pharmacy; 2. An administrative fine of 100,306.35 yuan was imposed on the pharmacy for defrauding the medical insurance fund of 22,290.30 yuan, and an administrative fine of 45,504.18 yuan was imposed on other general violations of 25,280.10 yuan, totaling 145,810.53 yuan; 3. Dissolve the designated service agreement of medical insurance in this pharmacy, and no longer accept its designated application for medical insurance within three years from the date of issuing the document. At present, the lost medical insurance fund of 47,570.40 yuan has been fully recovered.The administrative fine of 145,810.53 yuan has been paid in full.

V. Case of illegal use of medical insurance fund by Jishou Renmin North Road Branch of Yifeng Pharmacy Chain Co., Ltd. in Xiangxi, Hunan Province

In 2021, Hunan Xiangxi Medical Insurance Bureau found in daily inspection that Yifeng Pharmacy Chain Co., Ltd. Jishou Renmin North Road Branch had the problem of illegal drug expense settlement. Through data comparison, the inspectors found that during the period from January 1 to April 30, 2021, some drugs (such as vinegar corydalis yanhusuo, licorice tablets, acacia flowers, etc.) had no sales records and no inventory, but the actual reimbursement amount in the medical insurance system was 76,794.67 yuan. According to the "Regulations on the Supervision and Administration of the Use of Medical Insurance Funds", the local medical insurance department handled the following results: 1. Ordered the pharmacy to return the illegally used medical insurance funds, and imposed a fine of 1 times the loss of the medical insurance funds; 2, ordered the pharmacy rectification within a time limit. At present, the lost medical insurance fund of 76,794.67 yuan has been fully recovered, and the administrative fine of 76,794.67 yuan has been fully paid.

Six, Chongqing Kaizhou District Pharmaceutical Co., Ltd. illegal use of medical insurance fund case.

In December, 2021, during the daily inspection of designated medical institutions, Chongqing Kaizhou District Medical Security Bureau found that four designated retail pharmacies, including Kaizhou Pharmacy Drug Supermarket, Kaizhou Pharmacy Drug Supermarket Jiulong Road No.2 Store, Kaizhou Pharmacy Supermarket Zhaojiadian and Kaizhou Pharmacy Drug Supermarket Ankang Street Store, were suspected of taking employee medical insurance personal account funds for the insured. After investigation, four designated retail pharmacies under Chongqing Kaizhou Pharmaceutical Co., Ltd. took advantage of their units to purchase epidemic prevention materials, used their employees’ personal medical insurance accounts for settlement, and then issued tax bills in the name of their units and returned them to their units for reimbursement. There were irregularities in taking employees’ personal medical insurance account funds, involving the amount of employees’ personal medical insurance accounts of 14,869.90 yuan. According to the "Regulations on the Supervision and Administration of the Use of Medical Insurance Funds", the local medical insurance department handled the results as follows: 1. Ordered the four designated retail pharmacies involved in the case to return the medical insurance funds illegally used, and imposed a fine of 1 times the illegal amount; 2. Order the company to strengthen the publicity of medical insurance policies, conduct self-examination and rectification on the relevant problems existing in this inspection, and form a written report; 3. Five insured persons involved in the case did not understand the policy of medical insurance fund, so they gave warning education. At present, the lost medical insurance fund of 14,869.90 yuan has been fully recovered, and the administrative fine of 14,869.90 yuan has been fully paid.

7. The case of illegal use of medical insurance fund by people’s pharmacy in Haicheng District, Beihai City, Guangxi Zhuang Autonomous Region.

In February 2021, the Medical Security Bureau of Beihai City, Guangxi Zhuang Autonomous Region received a report clue, reflecting that the people’s pharmacy in Haicheng District of Beihai City was suspected of illegally using the medical insurance fund. After investigation, the pharmacy has forged false vouchers to exchange cash, placed illegal items and other violations, involving the illegal use of medical insurance funds of 71,847.05 yuan. According to the Service Agreement of Designated Retail Pharmacy for Employees’ Basic Medical Insurance in Beihai City (Monomer in 2020) and other relevant regulations, the results of the local medical insurance department are as follows: 1. Deduct the medical insurance fee of 71,847.05 yuan in the month when the pharmacy violated the regulations, and announce the violations of the pharmacy to the public; 2. Cancel the designated service agreement of medical insurance in this pharmacy, and no longer accept its designated application for medical insurance within three years. At present, the illegal use of medical insurance funds of 71,847.05 yuan has been fully recovered.

8. The case of illegal use of medical insurance fund by Wuhaotang Pharmacy in duyun city, Qiannan Prefecture, Guizhou Province.

In September, 2021, duyun city Medical Security Bureau in Qiannan Prefecture, Guizhou Province, found that Wuhaotang Pharmacy in duyun city was suspected of using medical insurance funds in violation of regulations. Investigators from duyun city Medical Insurance Bureau in Qiannan Prefecture found that there were many abnormal cases of large medical insurance card settlement in this pharmacy. Investigate and verify suspicious clues by collecting the data of pharmacy sales system, interviewing the person in charge of relevant designated retail pharmacies, and returning to the insured by telephone. After verification, the pharmacy provided medical insurance settlement for medical expenses incurred by five people, including Xiong Moumou, who was treated in a dental clinic in Duyun, involving a medical insurance fund totaling 41,880.00 yuan. According to the Service Agreement of Designated Retail Drugstore for Medical Security in Qiannan Prefecture and the Implementation Plan of duyun city on Carrying out Medical Insurance Credit Rating of Designated Medical Institutions, the local medical insurance department handled the results as follows: 1. Deducting the pharmacy’s illegal use of medical insurance fund of 41,880.00 yuan, and paying 2.5 times of liquidated damages, with the total deduction and liquidated damages of 146,580.00 yuan, which have all been returned to the medical insurance fund account; 2. From November 2, 2021, the medical insurance service agreement of this pharmacy will be dissolved and its violation will be announced to the public, and it will be included in the blacklist management of medical insurance credit rating; 3. Incorporate the legal representative and pharmacy manager of the pharmacy into the list of medical insurance untrustworthy persons; 4. Transfer the violation of the dental clinic involved to the local health department for handling.

9. The case of illegal use of medical insurance fund by Hongyan Pharmacy in Shannan City, Xizang Autonomous Region

In April, 2022, the Medical Security Bureau of Shannan City, Xizang Autonomous Region found that there was a phenomenon of "one person swiping cards continuously" in Hongyan Pharmacy in Shannan City. In June, 2022, Shannan Medical Insurance Bureau initiated an investigation into the illegal settlement of medical insurance fund by Hongyan Pharmacy. After investigation, Hongyan Pharmacy has fraudulent behaviors of swindling medicines and fictitious medical services, swindling the purchase of local products, health care products and other consumer goods into medicines and swiping medical insurance vouchers for settlement, and at the same time, there are illegal behaviors such as medical insurance vouchers for insured persons staying in the store and swiping cards regularly every day, involving medical insurance funds totaling 102,625.00 yuan. According to "People’s Republic of China (PRC) Social Insurance Law" and "Regulations on the Supervision and Administration of the Use of Medical Insurance Funds", the results of the local medical insurance department are as follows: 1. Order the pharmacy to return the defrauded medical insurance fund and impose a fine of 205,250.00 yuan twice the amount defrauded; 2. Suspend the medical services used by the medical insurance fund in this pharmacy for 6 months. At present, the lost medical insurance fund of 102,625.00 yuan has been fully recovered, and the twice administrative fine of 205,250.00 yuan has been fully paid.

X. Case of illegal use of medical insurance fund in a branch of Tiancheng Pharmacy, Karamay City, Xinjiang Uygur Autonomous Region

In July 2022, the Medical Security Bureau of Karamay City, Xinjiang Uygur Autonomous Region received a report clue, reflecting that a branch of Tiancheng Pharmacy in Karamay City was suspected of illegally using medical insurance funds. Verified by the Medical Insurance Bureau of Karamay District, Karamay City, the pharmacy has illegal behaviors such as swapping drugs, issuing false drug purchase documents to provide cash back for insured persons, involving illegal use of medical insurance funds of 155,775.69 yuan. According to the "Regulations on the Supervision and Administration of the Use of Medical Insurance Funds", the results of the local medical insurance department are as follows: 1. Recover the medical insurance funds illegally used by the pharmacy and impose a fine of 2 times the illegal amount; 2, ordered the pharmacy rectification within a time limit. At present, the lost medical insurance fund of 155,775.69 yuan has been fully recovered, and the administrative fine of 311,551.38 yuan has been fully paid.

CCTV News:At 10: 00 a.m. on August 31st, a press conference was held in the Ministry of Science and Technology for major national science and technology projects of large-scale advanced PWR and high-temperature gas-cooled reactor (hereinafter referred to as nuclear power projects). Qin Zhijun, deputy director of the Nuclear Power Department of the National Energy Administration and head of the special implementation management office, Zheng Mingguang, chief engineer of PWR disciplines and president of Shanghai Engineering Research and Design Institute, and Zhang Zuoyi, chief engineer of HTGR disciplines and president of Tsinghua University Institute of Nuclear Energy and New Energy, attended and introduced the special situation. Xie Min, Major Special Office of Ministry of Science and Technology, presided over the meeting.

The major nuclear power project is one of the 16 major national science and technology projects identified in the Outline of the National Medium and Long-term Science and Technology Development Plan (2006-2020). It is divided into two parts. One part is PWR, which is the third generation passive nuclear power technology with the main achievement of research and development, design and construction of CAP1400 demonstration project. The other is the high temperature reactor sub-item. The research, development, design and construction of 20MW high-temperature gas-cooled reactor demonstration project as the main achievement is one of the technical directions with the characteristics of the fourth generation nuclear power.

Up to now, 179 nuclear power projects have been approved, and the central budget has been approved at 11.399 billion yuan. Through special support, the technical level of China’s third-generation nuclear power has been significantly improved, the fourth-generation nuclear power technology has gradually moved to the forefront of the world, and the manufacturing of nuclear power-related equipment has been upgraded, which has taken a solid step on the road to achieving the goal of becoming a nuclear power.

Specific results include:

First, the special key tasks of nuclear power have progressed smoothly. The introduction, digestion and absorption of AP1000 have been basically completed, and the main work of thermal test of the first unit of Zhejiang Sanmen Support Project has been completed, and the loading is imminent. The CAP1400 design has passed the examination, and all the key tests have been completed, which has the conditions for construction. Most of the main equipment of high temperature gas-cooled reactor has been installed in place and is about to enter the debugging stage.

Second, in terms of equipment manufacturing, the ability and level have been greatly improved. A large number of major equipment, such as pressure vessels, steam generators, main pipelines, etc., have been localized; core equipment such as main pump of shielded motor, digital instrument control system and blasting valve have all been manufactured; control rod drive mechanism of high-temperature reactor and fuel loading and unloading system have been supplied. The acquisition of these achievements has significantly promoted equipment manufacturing enterprises to a higher level, enabling China to have the supply capacity of 6 to 8 sets of third-generation nuclear power equipment with an annual output. The comprehensive localization rate of third-generation nuclear power has increased from 2008.

Third, in terms of material development, a fundamental breakthrough has been achieved. A qualitative breakthrough has been made in the processing and manufacturing technology of key materials such as super-large forgings, 690 alloy pipes, pressure vessel seals and nuclear-grade zirconium materials; High temperature reactor fuel elements have been industrialized; The successful development of nuclear grade welding materials has changed the long-term dependence on imports of nuclear power welding materials in China. The first complete production line from sponge zirconium to finished pipes, plates, rods and strips was built, which provided strong support for the independent fuel research and development of CAP1400 and Hualong No.1..

Fourth, in terms of common technologies, it has laid a solid foundation for research and development. Give full play to the technological advantages of major nuclear power groups and related scientific research institutes, and jointly carry out in-depth analysis and research on common technologies such as reactor core and safety analysis key technology research, serious accident mechanism and phenomenology research, and nuclear power plant key material performance research, and build a number of international leading large-scale test benches and test facilities, which provide a guarantee for the design of new nuclear power models in China and the continuous improvement of nuclear power innovation and research and development capabilities.

Qin Zhijun said that the next step will continue to vigorously promote the implementation of major nuclear power projects. Reform the project subsidy method and further mobilize social forces to help the nuclear power industry tackle key problems. Focus on core technologies such as nuclear-grade pumps and valves, key components and basic materials, and accelerate the realization of fuel and software design and verification autonomy. Promote the construction of CAP1400 and do a good job in the demonstration project of high-temperature gas-cooled reactor. According to the highest international safety standards, we will further improve the evaluation and certification system of nuclear power technology application results to ensure the safety and reliability of products entering the nuclear power market. Improve the policy system for the application and promotion of special achievements, and comprehensively support the application of achievements in various ways such as "demonstration, subsidy and reward".

　　为全面反映2015年我国药品不良反应监测情况，促进临床合理用药，保障公众用药安全，依据《药品不良反应报告和监测管理办法》，国家食品药品监管总局组织国家药品不良反应监测中心编撰《国家药品不良反应监测年度报告(2015年)》。

　　一、药品不良反应监测工作进展

　　2015年，根据《药品不良反应报告和监测管理办法》有关要求，为督促药品生产企业建立健全药品不良反应报告和监测体系，切实履行报告和监测责任，国家食品药品监管总局发布了《药品不良反应报告和监测检查指南(试行)》，明确开展药品不良反应报告和监测工作检查的相关程序，促进药品不良反应报告和监测工作深入开展。

　　2015年，国家药品不良反应监测网络建设进一步深入，基层网络用户数量快速增长，全国已有28万余个医疗机构、药品生产经营企业注册为药品不良反应监测网络用户，并通过该网络报送药品不良反应报告。全国县级报告比例达到96.6%，每百万人口平均报告数量达到1044份，较2014年均有所增长，表明我国发现和收集药品不良反应信息的能力进一步增强。2015年，继续加强与世界卫生组织的合作及数据共享，得到世界卫生组织的高度赞扬和肯定。

　　2015年，药品不良反应报告和监测工作有序开展。通过日监测、周汇总、季度分析等方法加强对国家药品不良反应监测数据的分析评价，深入挖掘药品风险信号，对醒脑静注射液、酒石酸唑吡坦口服制剂、地塞米松注射剂等45个(类)品种进行了安全性评价，并采取了风险管理和沟通措施。编发《药物警戒快讯》12期，共计62条信息，涉及76个品种。继续推进药品不良事件聚集性信号处置工作，加强预警平台建设，提高预警工作效能，对重点关注的150多条药品不良事件聚集性信号及时进行处置，进一步保障公众用药安全。

　　II. Reporting of adverse drug reactions/incidents

　　(I) Overall report

　　1. Annual and monthly reports of adverse drug reactions/incidents in 2015

　　In 2015, the national adverse drug reaction monitoring network received 1.398 million copies of the "Adverse Drug Reaction/Event Report Form", an increase of 5.3% over 2014. From 1999 to 2015, the national adverse drug reaction monitoring network received nearly 9.30 million copies of the "Adverse Drug Reaction/Event Report Form".

　　2. Reporting of new and serious adverse drug reactions/incidents

　　In 2015, the national adverse drug reaction monitoring network received 393,734 new and serious adverse drug reaction/incident reports, an increase of 15.3% compared with 2014; the number of new and serious reports accounted for 28.2% of the total number of reports in the same period, an increase of 2.5% compared with 2014. The proportion of new and serious adverse drug reaction/event reports continued to increase, indicating that the overall quality and availability of adverse drug reaction reports in our country continued to improve.

　　3. Average case reporting per million population

　　The average number of cases reported per million population is one of the important indicators to measure the level of adverse drug reaction monitoring in a country. In 2015, the average number of cases reported per million population in our country was 1044, an increase of 5.4% compared with 2014.

　　4. County-level reporting of adverse drug reactions/incidents

　　The proportion of county-level reports of adverse drug reactions/events is one of the important indicators to measure the balanced development and coverage of adverse drug reaction monitoring in our country. In 2015, the proportion of county-level reports of adverse drug reactions/events nationwide was 96.6%, an increase of 2.2% compared with 2014.

　　5. Sources of adverse drug reactions/incident reports

　　According to the source of the report, 82.2% of the reports were from medical institutions, 16% from pharmaceutical distributors, 1.4% from pharmaceutical manufacturers, and 0.4% from individuals and other sources. In 2015, medical institutions were still the main source of reports; the number of reports from manufacturing enterprises was still low, but among the top 30 production enterprises with the number of reports, the number of domestic enterprises increased significantly.

　　6. Reporter occupation

　　According to the occupational statistics of reporters, doctors accounted for 53.0%, pharmacists accounted for 27.6%, nurses accounted for 14.6%, and other reports accounted for 4.8%. The occupational composition of reporters in 2014 was basically the same.

　　7. Reports of adverse drug reactions/incidents involving patients

　　According to the statistics of the age of the patients involved in the report, the reports of children under the age of 14 accounted for 9.9%, a slight decrease compared with 2014. The reports of the elderly over the age of 65 accounted for 21.5%, an increase of 1.6% compared with 2014. According to the statistics of the gender of the patients involved in the report, the ratio of male and female patients was close to 0.92:1, and there were slightly more females than males. The gender distribution trend was basically the same as in 2014.

　　8. Adverse drug reaction/incident reports involve the drug

　　According to the category of suspected drugs, chemical drugs accounted for 81.2%, traditional Chinese medicine accounted for 17.3%, and biological products (excluding vaccines) accounted for 1.5%. The number of reports of anti-infective drugs still ranked first, accounting for 44.9% of chemical drugs, a decrease of 1.3% from 2014, and the proportion of reports has been declining for 6 consecutive years. Cardiovascular system drugs accounted for 10.3% of the total number of chemical drugs reported, an increase of 0.1% from 2014, and an upward trend for 6 consecutive years. Electrolytes, acid-base balance and nutritional drugs all showed an upward trend for 6 consecutive years, and the proportion increased slightly compared with 2014.

　　According to the statistics of drug dosage forms, among the distribution of drug dosage forms involved in adverse drug reaction/incident reports in 2015, injections accounted for 61.3%, oral formulations accounted for 34.7%, and other formulations accounted for 4.0%. The proportion of injections increased by 3.5% compared with 2014, and the proportion of oral formulations decreased by 1.5%.

　　按照药品给药途径统计，2015年药品不良反应/事件报告涉及的药品给药途径分布中，静脉注射给药占57.9%、其他注射给药占3.2%、口服给药占35.8%、其他给药途径占3.1%，与2014年相比，总体给药途径分布无明显变化。

　　9.不良反应累及系统情况

　　2015年报告的药品不良反应/事件中，累及系统排名前三位的为皮肤及其附件损害(占27.3%)、胃肠系统损害(占26.2%)和全身性损害(占10.8%)，前三位之和占64.3%。化学药、中成药累及系统前三位排序与总体一致，但生物制品累及系统前三位与总体有所不同，依次是皮肤及其附件损害、全身性损害、免疫功能紊乱。

　　注射剂报告中累及系统排名前三位与总体报告一致，分别是皮肤及其附件损害(占32.5%)、胃肠系统损害(占19.1%)、全身性损害(占13.5%)，与2014年相比，全身性损害下降1.1%。口服制剂累及系统前三位为胃肠系统损害(占41.6%)、皮肤及其附件损害(占16.7%)、神经系统损害(12.9%)，与2014年基本持平。

　　10.药品不良反应/事件报告总体情况分析

　　2015年药品不良反应/事件报告总体情况与2014年相比未出现显著差异。在患者年龄分布中，老年患者不良反应报告比例依然出现增高态势，提示应继续关注老年人群用药安全。在剂型和给药途径分布中，化学药品注射制剂比例仍有小幅增加，提示应建立注射剂风险管理的长效机制，并应加强相关宣传、教育和研究工作。在化学药总体排名中，心血管系统用药所占比例有所增加，提示应继续加强心血管系统用药不良反应监测，及时发现风险并采取有效控制措施，保证患者的用药安全。

　　小贴士：

　　What is Adverse Drug Reaction Reporting and Monitoring? Why should the state establish a reporting system for adverse drug reactions?

　　Adverse drug reaction reporting and monitoring refers to the process of discovery, reporting, evaluation and control of adverse drug reactions. The main purpose of establishing an adverse drug reaction reporting system is to understand the occurrence of adverse drug reactions and detect new and serious adverse drug reactions in a timely manner. Due to the particularity of drugs, pre-market research is very limited, and its inherent risks need to be discovered through a wide range of clinical applications. Therefore, by strengthening the reporting and monitoring of adverse drug reactions, the potential inherent risks of drugs can be discovered in a timely manner, the risk-benefit ratio can be evaluated, and the safety information of drugs can be continuously improved to protect the public’s drug safety.

　　(Ii) Monitoring of essential drugs

　　1. Overall situation of national essential drug monitoring

　　In 2015, the overall situation of national essential drug monitoring remained basically stable. In 2015, the national adverse drug reaction monitoring network received a total of 575,000 reports of adverse reactions/events of national essential drugs (accounting for 41.1% of the overall reports in 2015), an increase of 1.9% over 2014. Among them, 37,000 cases were seriously reported, accounting for 6.4%, an increase of 0.8% over 2014. 83.1% of cases reported involving chemical drugs and biological products, and 16.9% of cases reported involving proprietary Chinese medicines.

　　2. Analysis of the situation of national essential medicines, chemicals and biological products

　　The "National Essential Drugs List (Primary Medical Institutions Equipped and Used Part) " (2012 Edition) includes chemical drugs (including biological products), divided into 25 categories and 317 varieties. In 2015, the National Adverse Drug Reaction Monitoring Network received 482,740 reports of adverse reactions/events of 359 specific varieties, of which 35,358 were serious reports, accounting for 7.3%.

　　2015年国家基本药物化学药品和生物制品报告按类别统计，报告数量排名前5位的分别是抗微生物药、心血管系统用药、抗肿瘤药、消化系统用药、镇痛/解热/抗炎/抗风湿/抗痛风药，占基本药物化学报告的73.1%。抗微生物的报告比例最高。化学药品(含生物制品)报告数量排名前五位的品种均为抗微生物药，分别是左氧氟沙星、头孢曲松、头孢呋辛、头孢他啶和青霉素。

　　2015年国家基本药物化学药品和生物制品不良反应/事件报告中，药品不良反应/事件累及系统排名前5位的是胃肠系统损害(占27.9%)、皮肤及其附件损害(占26.9%)、全身性损害(占9.5%)、中枢及外周神经系统损害(占9.1%)以及免疫功能紊乱和感染(占4.5%)；前5位不良反应例次之和占77.9%。

　　3.国家基本药物中成药情况分析

　　《国家基本药物目录(基层医疗卫生机构配备使用部分)》(2012版)中成药部分涉及内科用药、外科用药、妇科用药、眼科用药、耳鼻喉科用药、骨伤科用药6大类共203个品种。2015年全国药品不良反应监测网络收到该部分共203个相关品种的报告98,176例次，其中严重报告5,480例次，占5.6%。

　　2015年国家基本药物中成药部分六大类中，药品不良反应/事件报告总数由多到少依次为内科用药、骨伤科用药、妇科用药、耳鼻喉科用药、外科用药、眼科用药。其中内科用药报告总数占到总体报告数量的84.9%，内科用药构成比较大可能与内科用药临床使用量大，且基本药物目录中中药注射剂都属于内科用药有关。内科用药中排名前五位的分别是祛瘀剂、温理剂、开窍剂、清热剂、扶正剂，此五类药品报告占到内科用药报告数的88.9%。

　　2015年国家基本药物目录中成药部分药品不良反应/事件报告中，累及系统排名前三位的是皮肤及其附件损害(占29.0%)、胃肠系统损害(占23.8%)和全身性损害(占14.4%)。不同剂型报告累及系统中，注射剂不良反应/事件累及系统排名前三位的是皮肤及其附件损害(占21.1%)、全身性损害(占12.8%)、胃肠系统损害(占6.2%)，口服制剂累及系统排名前三位的是胃肠系统损害(占16.9%)、皮肤及其附件损害(占5.5%)、中枢及外周神经系统损害(占2.7%)。

　　2015年，根据药品不良反应监测风险信号，组织对可待因单方制剂、血栓通、血塞通注射制剂、缩宫素注射剂等基本药物品种开展了安全性评价，并采取了相应风险控制措施。

　　(三)抗感染药监测情况

　　1.抗感染药不良反应/事件报告总体情况

　　2015年全国药品不良反应监测网络共收到抗感染药的药品不良反应/事件报告51.3万例，其中严重报告2.84万例，占5.5%。抗感染药的药品不良反应/事件报告占2015年总体报告的36.7%。与2014年相比，2015年抗感染药报告数量同期增长1.2%，严重报告同期增加16.6%。严重报告构成比与2014年(4.8%)相比增加0.7%。

　　2.报告涉及患者情况及不良反应情况

　　2015年抗感染药药品不良反应/事件的总报告与总体报告年龄分布相比，1-4岁年龄段上升4.8%，45-64岁年龄段下降6%，65岁以上年龄段下降4.2%，其余各年龄段患者的比例浮动范围在4个百分点以内；与2014年抗感染药物的年龄分布相比基本一致。按报告涉及患者年龄统计，14岁以下儿童患者的报告占16.4%，高于整体数据儿童患者所占比例；65岁以上老年人的报告占17.3%。

　　In the 2015 report of adverse drug reactions/events of anti-infective drugs, the top three systems involved in adverse drug reactions/events were skin and its appendages (39.5%), gastrointestinal system damage (25.5%), and systemic damage (7.4%). The top three systems involved in oral anti-infective drugs were gastrointestinal system damage (44.6%), skin and its appendages damage (26.6%), and central and peripheral nervous system damage (6.9%); the top three systems involved in injection preparations were skin and its appendages damage (43.0%), gastrointestinal system damage (20.7%), and systemic damage (8.5%).

　　3. The report involves the situation of drugs

　　The 2015 anti-infective drug adverse reaction/incident reports involved 9 categories and 321 varieties, of which antibiotics accounted for 65.8%. The top five were cephalosporins (31.9%), macrolides (10.1%), penicillins (9.6%), beta-lactamase inhibitors (5.8%) and lincomycin (3.7%); synthetic antimicrobials accounted for 24.7%, mainly quinolones (18.4%) and nitroimidazoles (5.5%). There was no significant difference in the composition ratio of drugs and the composition of anti-infective drug reports in 2014.

　　In 2015, antibiotics accounted for 65.4% and synthetic antimicrobials 14.5% of serious adverse reactions/incident reports of anti-infective drugs, with no significant difference from the composition of anti-infective drug reports in 2014. The top five serious reports were cephalosporins (32.4%), quinolones (11.5%), penicillins (11.3%), anti-tuberculosis drugs (10.4%), and beta-lactamase inhibitors (7.6%). Compared with 2014, the ranking of quinolones rose to No. 2, and the ranking of penicillins fell to No. 3.

　　From the analysis of drug dosage forms, in 2015, injections accounted for 76.6%, oral formulations accounted for 16.8%, and other dosage forms accounted for 0.5%. Compared with the overall drug report, the proportion of injections (76.6%) was higher, which was basically the same as the distribution of dosage forms in 2014.

　　4. Analysis of anti-infective drug safety trends

　　In 2015, the total number of adverse reactions/events reported by anti-infective drugs increased compared with 2014, and the number of serious reports increased by 16.6%, which was higher than the increase in overall case reports in 2015. Compared with 2014, the proportion of adverse reactions/events reported by anti-infective drugs in 2015 decreased by 1.5%, the proportion of serious reports increased by 0.2%, and the proportion of serious reports increased by 0.7%.

　　小贴士：

　　What are the side effects of antibiotics?

　　Antibiotics are effective drugs for controlling various infections today, and they are one of the most commonly used drug categories. Nearly 100 kinds have been used. Their most common adverse reactions are as follows:

　　(1) Allergic reaction. Penicillin, streptomycin, pioneer mycin, etc. can cause allergic reactions in people, which can be life-threatening in severe cases. Allergic reactions caused by antibiotics are common for drug rashes, dermatitis and drug fever.

　　(2) Toxic reactions. Common toxic reactions caused by antibiotics include auditory nerve damage, hematopoietic system disorders, kidney damage, liver damage, and gastrointestinal reactions. The nature and extent of toxic reactions vary depending on the type of drug and individual patients.

　　(3) Drug resistance. Most bacteria can develop resistance to antibiotics. With the wide application of antibiotics and the overuse of antibiotics caused by irrational use of antibiotics, the number of drug-resistant strains is increasing, which affects the treatment of diseases, and even has serious consequences due to the lack of sensitive antibiotics to control infections.

　　(4) Local stimulation. Intramuscular injection of antibiotics can mostly cause local pain, and intravenous injection may also cause thrombophlebitis. It can be seen that antibiotics must be used rationally, and must not be used indiscriminately as a "panacea".

　　(IV) Monitoring of traditional Chinese medicine injections

　　1. Overall status of adverse reactions/incident reports of traditional Chinese medicine injections

　　In 2015, the safety status of traditional Chinese medicine injections was basically consistent with the overall situation in the country. In 2015, the national adverse drug reaction monitoring network received a total of 127,000 reports of traditional Chinese medicine injections, of which 9,798 were serious reports (7.7%). In 2015, the proportion of injections in adverse reaction/event reports of traditional Chinese medicine was 51.3%, a decrease of 2.1% compared with 2014.

　　2015年中药注射剂报告数量排名居前的类别是理血剂、补益剂、开窍剂、清热剂、解表剂、祛痰剂，共占中药注射剂总体报告的97.0%。报告数量排名前五名的药品分别是：清开灵注射剂、参麦注射剂、血塞通注射剂、双黄连注射剂、舒血宁注射剂。

　　2015年，中药注射剂严重报告主要涉及全身性损害、呼吸系统损害、皮肤及其附件损害等，包括过敏样反应、过敏性休克、寒战、发热、呼吸困难、胸闷、心悸、瘙痒、皮疹、恶心、呕吐等表现，与往年监测情况基本一致。

　　2.中药注射剂不良反应/事件报告合并用药情况

　　对2015 年中药注射剂总体报告排名前20 位药品(占全年中药注射剂报告87.6%)合并用药情况进行分析，其总体报告涉及合并用药占43.4%，严重报告涉及合并用药占56.5%，以上数据提示单独或联合其他药品使用中药注射剂均可出现不良事件，合并用药可能加大中药注射剂的安全风险。

　　三、用药安全提示

　　(一)关注老年患者用药问题

　　根据对2015年国家药品不良反应监测数据库收到的药品不良反应报告年龄分布情况分析，2015年65岁以上老年患者药品不良反应报告比例达21.5%，严重报告比例达28.7%。国家药品不良反应监测数据库分析显示，自2009年以来，该两项比例持续7年上升，老年患者用药安全问题需引起特别关注。一般来说，老年人脏器功能退化，新陈代谢减慢，容易发生药品不良反应；老年人往往身患一种以上的疾病，有些老年人还服用一些保健品等，所以老年人用药要特别慎重，选择药品时要多咨询医生，注意给药途径和时间、加强用药前和用药期间监护。

　　小贴士：

　　老年人使用抗菌药物应注意的相关问题及用药十忌原则：

　　老年人因肝肾功能衰退，对药物的耐受性降低，尤其是一些活性较强的药物，极易产生毒副作用和过敏反应。抗菌药物在人体吸收以后，多由肝脏和肾脏解毒、排泄。因此，肝肾功能不全的老人，在用这些药时需慎重，不宜长期或大剂量应用。故长期、大剂量使用这些抗菌药物，对老年人是非常不利。老年用药十忌原则：一忌随意滥用；二忌品种过多；三忌时间太长；四忌不遵医嘱；五忌生搬硬套；六忌乱用偏方、秘方、验方；七忌滥用补药；八忌更换过频；九忌嗜药成瘾；十忌联用毒副作用强的药物。

　　(二)关注心血管系统用药安全

　　2015年化学药总体排名中，心血管系统用药占10.3%(排名第二)，仅次于抗感染药，连续5年呈上升趋势。按照化学药剂型排名，口服制剂前20名的品种中心血管系统用药为7个，与2014年相比心血管系统用药所占比例均有所增长。随着我国居民生活水平的逐步提高，高血压、冠心病、高血脂等心血管疾病的发病率亦呈增长的趋势，心血管系统用药尤其是口服制剂使用也随之越来越广泛。相关数据显示，近20年间，我国心血管病死亡率一直呈上升趋势，且35岁-55岁的中青年男性冠心病死亡率增加最快，心血管用药安全应引起格外关注。

　　小贴士：

　　如何合理使用心血管药物？

　　高血压、冠心病、心律失常、心力衰竭是临床最常见的心血管疾病。在治疗心血管疾病时，要注意鉴别疾病类型和分期，恰当的选择最适合病情的药物，以求达到最佳治疗效果和最大程度的降低不良反应的发生。在用药过程中还应注意一些特殊情况，例如：高血压患者应加强血压监测，确定最佳服药时间，在服用降压药时要谨防“首剂反应”，服药过程中忌频繁换药，患者用药前应仔细阅读所服药物的说明书，掌握心血管药物适应症、禁忌症、不良反应，注意合理用药。

　　(三)关注基层医疗机构注射剂使用安全

　　2015年化学药不良反应/事件报告中，注射剂所占比例为62.9%；中药不良反应/事件报告中，注射剂所占比例为51.3%；而严重药品不良反应报告的给药途径以静脉注射为主，占70%以上。国家药品不良反应监测数据分析显示，部分中药注射剂的不良反应主要来源于基层医疗卫生机构。注射剂的不良反应主要表现为过敏及类过敏反应，部分病例可出现过敏性休克等严重过敏反应，需要紧急救治。基层医疗卫生机构的救治设备、设施较为有限，医护人员救治经验和能力相对缺乏，影响抢救效果及预后，基层医疗机构的输液风险值得关注。

　　小贴士：

　　如何合理使用注射剂？

　　静脉输液是高风险、高获益的临床用药方法，起效迅速，易于调节给药剂量和速度，可恒定维持治疗所需的药物浓度。如能合理使用，静脉输液的临床获益大于风险；过度使用时，静脉输液的风险则明显增加，甚至可能超过临床获益，给患者带来不必要的风险及经济损失。国内绝大多数医疗机构都有门诊输液，门诊输液几乎成了中国老百姓的就医习惯，长期以来人们形成了“输液好、输液快”的错误认识和就医习惯。用药要遵循能不用就不用、能少用就不多用、能口服不肌注、能肌注不输液的原则。

　　(四) 关注合理用药问题

　　据统计，2008年至2015年国家发布的《药品不良反应信息通报》总计66个药品中，27个存在明显不合理用药情况；如：2015年药品不良反应信息通报(第69期)中提醒注射用头孢硫脒，存在比较严重的不合理用药现象，包括单次超剂量、日剂量超量给药，未分次给药等，增加了患者发生严重不良反应的风险。2015年，国家药品不良反应监测中心对国内医学文献中涉及不合理用药情况进行了系统分析，结果显示抗菌药、静脉输液和中药注射剂不合理用药问题突出。

　　小贴士：

　　合理用药十大提示？

　　1.优先使用基本药物；

　　2.遵循能不用就不用、能少用就不多用，能口服不肌注、能肌注不输液的原则；

　　3.买药要到合法医疗机构和药店，注意区分处方药和非处方药，处方药必须凭执业医师处方购买；

　　4.阅读药品说明书，特别要注意药物的禁忌、慎用、注意事项、不良反应和药物间的相互作用等事项；

　　5.处方药要严格遵医嘱，切勿擅自使用。特别是抗菌药物和激素类药物，不能自行调整用量或停用；

　　6.任何药物都有不良反应，非处方药长期、大量使用也会导致不良后果；

　　7.孕期及哺乳期妇女用药要注意禁忌；儿童、老人和有肝脏、肾脏等方面疾病的患者，用药应谨慎，用药后要注意观察；从事驾驶、高空作业等特殊职业者要注意药物对工作的影响；

　　8. Drugs should be stored scientifically and properly; beware of misuse and misuse by children and mentally ill persons;

　　9. Vaccination is the most effective and economical measure to prevent some infectious diseases, and the state provides free first-class vaccines.

　　10. Health foods cannot replace medicines.

　　IV. Relevant risk control measures

　　According to the adverse drug reaction monitoring data and evaluation results in 2015, the State Food and Drug Administration has taken corresponding risk control measures in a timely manner for drugs found to have potential safety hazards to ensure the safety of public medication.

　　(1) Issued the 4th issue of the "Adverse Drug Reaction Information Circular", reporting serious adverse reactions such as metoclopramide, atypical antipsychotics, Chinese and Western medicine compound preparations, and ceftiramide for injection, timely reminding of drug safety risks.

　　(2) Published 12 issues of "Pharmacovigilance Alert", reporting 62 pieces of foreign drug safety information such as suicide risk of pregabalin and severe skin reactions of ziprasidone.

　　(3) According to the monitoring and evaluation results, the organization revised the instructions of 40 (categories) of drugs such as Xuesaitong, Naoluotong Capsule, and Trikrutin Injection.

　　V. Relevant Instructions

　　(1) The data in this annual report is derived from the data reported by each region from January 1, 2015 to December 31, 2015 in the National Adverse Drug Reaction Monitoring Database.

　　(2) Like most countries, the data collected by the adverse drug reaction monitoring database in our country has limitations, such as underreporting, irregular filling, lack of detailed information, and inability to calculate the incidence of adverse reactions.

　　(III) At the time of the completion of this annual report, some of the serious reports and death reports were still under investigation and evaluation. All statistical results were a true reflection of the data collection situation, and some issues did not represent the final evaluation results.

　　(Iv) The number of adverse drug reactions/events reported is influenced by many factors such as the amount of the drug used and the incidence of adverse drug reactions. Therefore, the ranking of the number of adverse drug reactions/events reported is only a direct reflection of the number of reported data, and does not represent the incidence of adverse reactions.

　　(V) This annual report does not include surveillance data on vaccine adverse reactions/events.